Evidence map›Paper›PMID 35445344›Full record

ArticleInternational ophthalmology2022

Intermediate-term outcomes of combined phacoemulsification and Aurolab aqueous drainage implant in eyes with refractory glaucoma and coexistent cataract.

Sharmila Rajendrababu, George Varghese Puthuran, Laxmi Ananya Alia, Mohammed Sithiq Uduman, Hiruni Kaushalya Wijesinghe

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Article in International ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sharmila RajendrababuAravind Eye Hospital and Post Graduate Institute of Ophthalmology, Madurai, Tamil Nadu, 625020, India. sharmila@aravind.org.
George Varghese PuthuranAravind Eye Hospital and Post Graduate Institute of Ophthalmology, Madurai, Tamil Nadu, 625020, India.
Laxmi Ananya AliaAravind Eye Hospital and Post Graduate Institute of Ophthalmology, Madurai, Tamil Nadu, 625020, India.
Mohammed Sithiq UdumanAravind Eye Hospital and Post Graduate Institute of Ophthalmology, Madurai, Tamil Nadu, 625020, India.
Hiruni Kaushalya WijesingheAravind Eye Hospital and Post Graduate Institute of Ophthalmology, Madurai, Tamil Nadu, 625020, India.
Aravind Eye Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the efficacy and safety of non-valved Aurolab aqueous drainage implant (AADI) surgery combined with phacoemulsification in eyes with refractory glaucoma and coexistent cataract.

methodsIncluded patients of 18 years or older who underwent combined AADI-Phacoemulsification from June 2015 to January 2017 with at least 12 months of consecutive follow-up. The best-corrected visual acuity, intraocular pressure (IOP), and the number of IOP-lowering medications were recorded at baseline, 2 weeks, 1, 3, 6, 12, 18, and 24 months. Cumulative probability of success was defined as IOP < 18 mmHg or 30% reduction from the baseline at two consecutive postoperative visits after 3-months. Loss of light perception or reoperation for uncontrolled glaucoma or a complication was considered failure apart from IOP criteria.

resultsSeventeen eyes of 17 patients with a mean follow-up of 22.6 ± 4.0 months were included. Baseline IOP and ocular hypotensive drugs reduced significantly from 27.9 ± 7.6 mmHg to 14.0 ± 3.0 mmHg (p < 0.001) and 3.24 ± 0.7 to 1.33 ± 1.1 (p = 0.001), respectively, at 24 months. Cumulative probability of qualified success was 71.4% (95% Confidence Interval [CI] 40.6-88.2%) at 3 months and was maintained from 6 months onwards at 64.3% (95% CI 34.3-83.3%), up to 2 years. Intravitreal steroid was injected in one eye (5.9%) of chronic cystoid macular edema, and tube repositioning was done in another for focal corneal decompensation.

conclusionsCombined AADI-Phacoemulsification surgery is a safe and effective option in providing favorable visual and IOP outcomes at an affordable cost in eyes with refractory glaucoma and coexistent cataract.

Indexed as

CataractGlaucomaGlaucoma Drainage ImplantsPhacoemulsificationFollow-Up StudiesHumansIntraocular PressureRetrospective StudiesTreatment OutcomeVisual AcuityAurolab aqueous drainage deviceNon-valved glaucoma drainage devicesPhacoemulsification

Identifiers

PMID35445344
OpenAlexW4224255172

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.