ArticleProbiotics and antimicrobial proteins2022
Probiotic Potential of Bacillus licheniformis and Bacillus pumilus Isolated from Tibetan Yaks, China.
Article in Probiotics and antimicrobial proteins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 34 citations in OpenAlex.
- Evaluating the probiotic potential of Bacillus pumilus HFS2 isolated from the gut microbiota of Heteropneustes fossilis for aquaculture applications.Journal, genetic engineering & biotechnology · 2026Article
- Gut microbiota and meat quality in ruminants: a review of mechanisms and microbiota-targeted interventions.Food science of animal resources · 2026Review
- Genomic and Phenotypic Characterization of the Probiotic Potential and Safety of Bacillus velezensis CH3-2 Isolated from Chahua Chicken.Probiotics and antimicrobial proteins · 2026Article
- Article
- Supplementation of a Dietary Probiotics Blend can Enhance Growth Performance in Guiqian Semi-Fine Wool Sheep by Modulating Rumen Microbiota and Immune Function.Probiotics and antimicrobial proteins · 2026Article
- Comparative gut microbiome composition and predicted microbial functions in captive and free-range yaks (Veterinary world · 2026Article
- Isolation and Probiotic Functions ofBiology · 2025Article
- Tannic acid-iron stabilized probiotic silver nano hybrids: Multi-target gut microbiota modulation and intestinal barrier restoration.Materials today. Bio · 2025Article
- Targeted Screening of Fiber Degrading Bacteria with Probiotic Function in Herbivore Feces.Probiotics and antimicrobial proteins · 2025Article
- Characterization of the resistome and antibiotic-resistant bacteria in top soil improvers and irrigation waters devoted to food production: a case study from Italy.Environmental science and pollution research international · 2025Article
- Article
- Phenotypic and genotypic characterization of probiotic strains in the context of antimicrobial resistance.Frontiers in veterinary science · 2025Article
- Identification and Bioactivity Analysis of a NovelAntibiotics (Basel, Switzerland) · 2024Article
- Impact of Bacillus licheniformis from yaks following antibiotic therapy in mouse model.Applied microbiology and biotechnology · 2024Article
- The Therapeutic Effects of Lactic Acid Bacteria Isolated from Spotted Hyena on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.Nutrients · 2024Article
- Defined Pig Microbiota Mixture as Promising Strategy against Salmonellosis in Gnotobiotic Piglets.Animals : an open access journal from MDPI · 2024Article
- Article
- Probiotic Potential of Bacillus amyloliquefaciens Isolated from Tibetan Yaks.Probiotics and antimicrobial proteins · 2024Article
- ProbioticFrontiers in microbiology · 2024Article
- Coadministration of Lactulose with Probiotics Ameliorates Loperamide-Induced Constipation in Mice.Preventive nutrition and food science · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Yak (Bos grunniens) inhabit an oxygen-deficient environment at the altitude of 3000 m on the Tibetan Plateau, with a distinctive gut micro-ecosystem. This study evaluated the probiotic potential and physiological property of Bacillus licheniformis and Bacillus pumilus isolated from the gut of yaks. Four strains, two Bacillus licheniformis (named D1 and D2) and two Bacillus pumilus (named X1 and X2), were isolated and identified by 16S rRNA sequencing. All strains had potential antibacterial ability against three indicator pathogens: Escherichia coli C83902, Staphylococcus aureus BNCC186335, and Salmonella enteritidis NTNC13349. The antioxidant activity test showed that D2 sample showed the highest antioxidant activity. Furthermore, all four strains had a higher hydrophobicity, auto-aggregation, acid tolerance, bile tolerance, and antibiotic sensitivity, which all contribute to their survival in the gastrointestinal tract and clinical utility. The animal experimentation (40 KM mice, equally divided into five groups of eight mice each) showed that the strain supplementation not only increased daily weight gain and reduced feed conversion ratio, but also increased the length of the jejunum villi and the value of the V/C (Villi/Crypt). In conclusion, this is the first study demonstrated the probiotic potential of Bacillus licheniformis and Bacillus pumilus isolated from yaks, providing a theoretical basis for the clinical application and development of new feed additives.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.