Evidence map›Paper›PMID 35445205›Full record

ArticleCell reports methods2022

A versatile toolbox for studying cortical physiology in primates.

Karam Khateeb, Julien Bloch, Jasmine Zhou, Mona Rahimi, Devon J Griggs, Viktor N Kharazia, Minh N Le, Ruikang K Wang, Azadeh Yazdan-Shahmorad

Open access · goldAbstract read
In one paragraph

Article in Cell reports methods, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Towards maximizing optical access through Smart Dura.Journal of neural engineering · 2026
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  12. Review
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  14. Review
  15. A Neural Implant Design Toolbox for Nonhuman Primates.Journal of visualized experiments : JoVE · 2024
    Article
  16. Review
  17. Review
  18. Neuroprotective Effects of Electrical Stimulation Following Ischemic Stroke in Non-Human Primates.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2022
    Article
  19. Demonstration of an Optimized Large-scale Optogenetic Cortical Interface for Non-human Primates.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Karam KhateebDepartment of Bioengineering, University of Washington, Seattle, WA 98195, USA.
Julien BlochDepartment of Bioengineering, University of Washington, Seattle, WA 98195, USA.
Jasmine ZhouDepartment of Bioengineering, University of Washington, Seattle, WA 98195, USA.
Mona RahimiWashington National Primate Research Center, Seattle, WA 98195, USA.
Devon J GriggsWashington National Primate Research Center, Seattle, WA 98195, USA.
Viktor N KharaziaDepartment of Physiology and Center for Integrative Neuroscience, University of California, San Francisco, San Francisco, CA 94143, USA.
Minh N LeDepartment of Bioengineering, University of Washington, Seattle, WA 98195, USA.
Ruikang K WangDepartment of Bioengineering, University of Washington, Seattle, WA 98195, USA.
Azadeh Yazdan-ShahmoradDepartment of Bioengineering, University of Washington, Seattle, WA 98195, USA.
University of Washington · USUniversity of California, San Francisco · US

Funding

Washington National Primate Research CenterP51OD010425 · OD · UNIVERSITY OF WASHINGTON · PI Mari Ostendorf · 2012 to 2026
$201.8M
Interdisciplinary Engineering Career Development Center in Movement and Rehabilitation SciencesK12HD073945 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DEWALD, JULIUS P, REINKENSMEYER, DAVID JAY · 2012 to 2021
$7.9M
Engineering neuroplasticity using volitional control of activity-dependent optogenetic stimulation in macaque sensorimotor cortexR01NS119395 · NINDS · UNIVERSITY OF WASHINGTON · PI YAZDAN SHAHMORAD, AZADEH · 2021 to 2025
$3.9M
Ultra-wide field optical coherence tomography based angiography for imaging diabetic retinopathyR01EY028753 · NEI · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2018 to 2021
$2.2M
Smart Dura: A Functional Large-scale, High-Density Optoelectric Dura for Non-Human PrimatesR01NS116464 · NINDS · CARNEGIE-MELLON UNIVERSITY · PI CHAMANZAR, MAYSAMREZA · 2020 to 2024
$2.0M
NEI NIH HHS R01 EY028753NICHD NIH HHS K12 HD073945NIH HHS P51 OD010425NINDS NIH HHS R01 NS116464NINDS NIH HHS R01 NS119395
6 · The paper itself

Abstract

Lesioning and neurophysiological studies have facilitated the elucidation of cortical functions and mechanisms of functional recovery following injury. Clinical translation of such studies is contingent on their employment in non-human primates (NHPs), yet tools for monitoring and modulating cortical physiology are incompatible with conventional lesioning techniques. To address these challenges, we developed a toolbox validated in seven macaques. We introduce the photothrombotic method for inducing focal cortical lesions, a quantitative model for designing experiment-specific lesion profiles and optical coherence tomography angiography (OCTA) for large-scale (~5 cm

Indexed as

BrainElectric Stimulation TherapyAnimalsMacacaPrimates

Identifiers

PMID35445205
PMCPMC9017216
OpenAlexW4221023291

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.