Evidence map›Paper›PMID 35445078›Full record

ArticleFrontiers in molecular biosciences2022

Structural and Enzymological Evidence for an Altered Substrate Specificity in Okur-Chung Neurodevelopmental Syndrome Mutant CK2α

Christian Werner, Alexander Gast, Dirk Lindenblatt, Anna Nickelsen, Karsten Niefind, Joachim Jose, Jennifer Hochscherf

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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  9. Predictive functional, statistical and structural analysis ofFrontiers in molecular biosciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Christian WernerDepartment of Chemistry, Institute of Biochemistry, University of Cologne, Cologne, Germany.
Alexander GastInstitute of Pharmaceutical and Medicinal Chemistry, University of Münster, Münster, Germany.
Dirk LindenblattDepartment of Chemistry, Institute of Biochemistry, University of Cologne, Cologne, Germany.
Anna NickelsenInstitute of Pharmaceutical and Medicinal Chemistry, University of Münster, Münster, Germany.
Karsten NiefindDepartment of Chemistry, Institute of Biochemistry, University of Cologne, Cologne, Germany.
Joachim JoseInstitute of Pharmaceutical and Medicinal Chemistry, University of Münster, Münster, Germany.
Jennifer HochscherfDepartment of Chemistry, Institute of Biochemistry, University of Cologne, Cologne, Germany.
University of Cologne · DEUniversity of Münster · DEInstitute for Biomedical and Pharmaceutical Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Specific

Indexed as

acidophilic substrate specificityanion binding sitecasein kinase 2CSNK2A1 geneokur-chung neurodevelopmental syndrome (OCNDS)P+1 loopprotein kinase CK2substrate recognition

Identifiers

PMID35445078
PMCPMC9014129
OpenAlexW4226152197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.