ReviewFrontiers in nutrition2022
Extra-Oral Taste Receptors-Function, Disease, and Perspectives.
Review in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 62 citations in OpenAlex.
- Trial
- Taste Modulation by Umami Compounds: Mechanisms, Sensor-Based Evaluation, and Pharmaceutical Applications in Bitterness Suppression.Sensors (Basel, Switzerland) · 2026Review
- Article
- Sweet and umami TAS1R receptors: from molecular recognition to physiological function.Chemical senses · 2026Review
- Steroid Hormones Are Potent and Putatively Endogenous Activators of Human Bitter Taste Receptors.Annals of the New York Academy of Sciences · 2026Article
- Parthenolide promotes glucagon-like peptide-1 secreting in human Caco-2 cells via regulation of bitter taste receptor-induced of calcium signaling.Molecular and cellular biochemistry · 2026Article
- Endocrine-Taste Crosstalk: A Scoping Review on Thyroid Dysfunction and Its Genetic Links to Taste Receptors With Dysgeusia.International journal of endocrinology · 2026Review
- Taste receptor downregulation in diet-induced obesity reveals circumvallate papillae-specific taste-inflammatory networks.Frontiers in nutrition · 2026Article
- Recent Advances and Unaddressed Challenges in Biomimetic Olfactory- and Taste-Based Biosensors: Moving Towards Integrated, AI-Powered, and Market-Ready Sensing Systems.Sensors (Basel, Switzerland) · 2025Review
- Beyond Sugar: A Holistic Review of Sweeteners and Their Role in Modern Nutrition.Foods (Basel, Switzerland) · 2025Review
- Expression and structural analysis of taste receptor genes in Iberian and Duroc pigs.Genetics, selection, evolution : GSE · 2025Article
- TAS2R38 gene methylation is associated with syndrome Coronavirus 2 (SARS-CoV-2) infection and clinical symptoms.Scientific reports · 2025Article
- Bitter Taste Receptors 38 and 46 Regulate Intestinal Peristalsis.International journal of molecular sciences · 2025Article
- Article
- Taste receptors and their ecological niches: cats, dogs, and other vertebrates.Chemical senses · 2025Review
- Bitter taste receptors.Chemical senses · 2025Review
- Postoral receptors and alimentary taste: implications for energy intake and appetite.Chemical senses · 2025Review
- Bitter taste receptors as sensors of gut luminal contents.Nature reviews. Gastroenterology & hepatology · 2025Review
- Review
- Ectopic taste receptors in animal physiology: evolutionary conservation and functional diversification.Frontiers in cell and developmental biology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Taste perception is crucial for the critical evaluation of food constituents in human and other vertebrates. The five basic taste qualities salty, sour, sweet, umami (in humans mainly the taste of L-glutamic acid) and bitter provide important information on the energy content, the concentration of electrolytes and the presence of potentially harmful components in food items. Detection of the various taste stimuli is facilitated by specialized receptor proteins that are expressed in taste buds distributed on the tongue and the oral cavity. Whereas, salty and sour receptors represent ion channels, the receptors for sweet, umami and bitter belong to the G protein-coupled receptor superfamily. In particular, the G protein-coupled taste receptors have been located in a growing number of tissues outside the oral cavity, where they mediate important processes. This article will provide a brief introduction into the human taste perception, the corresponding receptive molecules and their signal transduction. Then, we will focus on taste receptors in the gastrointestinal tract, which participate in a variety of processes including the regulation of metabolic functions, hunger/satiety regulation as well as in digestion and pathogen defense reactions. These important non-gustatory functions suggest that complex selective forces have contributed to shape taste receptors during evolution.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.