Evidence map›Paper›PMID 35444696›Full record

ArticleJournal of oncology2022

Association between the Expression Levels of MicroRNA-101, -103, and -29a with Autotaxin and Lysophosphatidic Acid Receptor 2 Expression in Gastric Cancer Patients.

Sara Tutunchi, Saeedeh Akhavan, Ghodratollah Panahi, Mina Zare, Amirnader Emami Razavi, Reza Shirkoohi

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Sara TutunchiDepartment of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Postal Code: 8915173143.ORCID https://orcid.org/0000-0002-1407-9691
Saeedeh AkhavanDepartment of Biology, School of Basic Sciences, Science and Research Branch, Islamic Azad University (IAU), Tehran, Iran Postal Code: 1477893855.ORCID https://orcid.org/0000-0002-6477-7738
Ghodratollah PanahiDepartment of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran Postal Code: 1417653761.ORCID https://orcid.org/0000-0001-8338-4633
Mina ZareRecombinant Protein Laboratory, Department of Biochemistry, Shiraz University of Medical Sciences, Shiraz, Iran Postal Code: 7134845794.ORCID https://orcid.org/0000-0003-1061-4439
Amirnader Emami RazaviIran National Tumor Bank, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran Postal Code: 1419733141.ORCID https://orcid.org/0000-0001-6811-6075
Reza ShirkoohiCancer Biology Research Center, Cancer Research Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran Postal Code: 1419733141.ORCID https://orcid.org/0000-0003-1642-0483
Tehran University of Medical Sciences · IRImam Khomeini Hospital · IRIslamic Azad University, Science and Research Branch · IRShahid Sadoughi University of Medical Sciences and Health Services · IRShiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Gastric cancer (GC) is regarded as the most prevalent malignancy with the high mortality rate, worldwide. However, gastroscopy, a biopsy of suspected sample, and detecting CEA, CA19-9, and CA72-4 are presently used, but these diagnostic approaches have several limitations. Recently, microRNAs as the most important member of noncoding RNAs (ncRNAs) have received attention; recent evidence demonstrates that they can be used as the promising candidate biomarkers for GC diagnosis. We aimed to investigate the association between the microRNA-29a, -101, and -103 expression and autotaxin (ATX) and lysophosphatidic acid receptor 2 (LPA2) expression in GC patients. Results: The expression levels of miR-29 and miR-101 were significantly lower ( Conclusion: It seems that determining the expression level of miR-101, -103, and -29, as the novel diagnostic biomarkers, has diagnostic value to distinguish GC patients from healthy individuals.

Identifiers

PMID35444696
PMCPMC9015865
OpenAlexW4223552915

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.