ReviewFrontiers in psychiatry2022
Adipose Tissue Compartments, Inflammation, and Cardiovascular Risk in the Context of Depression.
Review in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Adipose tissue distribution in metabolic disease: depot-specific biology, clinical assessment, and therapeutic remodeling.Frontiers in endocrinology · 2026Review
- A body shape index combined with the triglyceride-glucose index for cardiovascular risk prediction in overweight and obese Chinese adults.Frontiers in cardiovascular medicine · 2026Article
- Neutrophil-to-high-density lipoprotein cholesterol ratio (NHR) mediates the relationship between abdominal fat index and depression in a cross-sectional study.BMC psychiatry · 2025Article
- Investigating the visceral adiposity-major depressive disorder link: a cross-sectional NHANES 2011-2014 analysis and Mendelian randomization study.Eating and weight disorders : EWD · 2025Article
- Effect of Visceral Adipose Tissue on Major Depressive Disorder: A Mendelian Randomisation Research.Actas espanolas de psiquiatria · 2025Article
- The relationship between VAI, LAP, and depression and the mediation role of sleep duration-evidence from NHANES 2005-2020.BMC psychiatry · 2025Article
- The relationship between visceral adipose tissue and osteoarthritis among older adults: evidence from the NHANES 1999-2018.Frontiers in nutrition · 2025Article
- Major depression recurrence is associated with differences in obesity-related traits in women, but not in men.European psychiatry : the journal of the Association of European Psychiatrists · 2024Article
- Depression Predicts Cardiac Cachexia in Heart Failure Patients.Biological research for nursing · 2023Article
- Post-Bariatric Plastic Surgery: Abdominoplasty, the State of the Art in Body Contouring.Journal of clinical medicine · 2022Article
- Twelve-month outcomes in overweight/obese users with mental disorders following a multi-element treatment including diet, physical activity, and positive thinking: The real-world "An Apple a Day" controlled trial.Frontiers in psychiatry · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The neurobiological and behavioral underpinnings linking mental disorders, in particular, major depressive disorder (MDD), with cardiovascular disorders are a matter of debate. Recent research focuses on visceral (intra-abdominal and epicardial) adipose tissue and inflammation and their impact on the development of cardiometabolic disorders. Intra-abdominal adipose tissue is defined as an endocrine active fat compartment surrounding inner organs and is associated with type 2 diabetes mellitus, a risk factor for the later development of cardiovascular disorders. Epicardial (pericardial) adipose tissue is a fat compartment surrounding the heart with close proximity to the arteries supporting the heart. Visceral adipose tissue (VAT) is an important source of inflammatory mediators that, in concert with other risk factors, plays a leading role in cardiovascular diseases. In conjunction with the behavioral (physical inactivity, sedentary lifestyle), psychological (adherence problems), and hormonal (dysfunction of the hypothalamus-pituitary-adrenal axis with subsequent hypercortisolism) alterations frequently accompanying MDD, an enhanced risk for cardiovascular disorders results.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.