ArticleClinical interventions in aging2022
Relationship Between Preoperative Hypoalbuminemia and Postoperative Pneumonia Following Geriatric Hip Fracture Surgery: A Propensity-Score Matched and Conditional Logistic Regression Analysis.
Article in Clinical interventions in aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Hypoalbuminaemia contributes to postoperative pulmonary complications and mortality: a systematic review and meta-analysis.BMC anesthesiology · 2026Pooled it
- Prevalence and associated risk factors of pneumonia following surgery for geriatric osteoporotic fracture: A nationwide cross-sectional study of China.Scientific reports · 2026Article
- Silent threat: how preoperative albumin levels affect geriatric cancer surgery outcomes?BMC surgery · 2026Article
- Pneumonia Risk in Institutionalized Older Adults With Severe Functional Dependency: An Exploratory Analysis Using Standardized Long-Term Care Assessment Data.Geriatrics & gerontology international · 2026Observational
- Development and Validation of a Robust Prediction Model for Postoperative Pneumonia in Elderly Patients with Hip Fracture: Integrating Frailty, Nutrition, and Comprehensive Risk Assessment.Risk management and healthcare policy · 2026Article
- Peri-operative nutrition in femoral neck fracture arthroplasty: a pragmatic framework to mitigate dual-hit catabolism and improve outcomes.Orthopedic reviews · 2026Article
- Nutrition-related clinical laboratory indicators in perioperative management of geriatric hip fractures: a narrative review from risk stratification to precision intervention.Frontiers in nutrition · 2026Review
- Risk factors for pneumonia, hepatic encephalopathy, and acute kidney injury in patients with hepatitis B virus-related acute-on-chronic liver failure.Frontiers in medicine · 2026Article
- Treg/Th17 imbalance and its association with frailty in elderly patients with community-acquired pneumonia.Frontiers in medicine · 2026Article
- Elevated neutrophil percentage-to-albumin ratio is associated with postoperative pneumonia in patients with hip fractures.Frontiers in medicine · 2026Article
- Association of inflammatory markers and surgical intervention with postoperative pneumonia in patients with femoral intertrochanteric fracture: A propensity score-matched cohort study.Journal of orthopaedics · 2025Article
- Immune biomarkers for predicting postoperative pneumonia following hip fracture surgery.Biomarkers in medicine · 2025Article
- Procalcitonin as a biomarker for postoperative pneumonia: a study on dynamics following cardiopulmonary bypass in adults.BMC cardiovascular disorders · 2025Article
- Serum Albumin-Creatinine Ratio and Anthracycline Cardiotoxicity in Patients with Cancer.Journal of clinical medicine · 2025Article
- Nomogram for predicting the development of pneumonia after colorectal cancer surgery.Scientific reports · 2025Article
- Frequency and Predictors of Pneumonia After Isolated Coronary Artery Bypass Grafting (CABG): A Single-Center Study.Diagnostics (Basel, Switzerland) · 2025Article
- Development of an Online Nomogram for Predicting Postoperative Hypoalbuminemia in Older Adults Following Femoral Neck Fractures.Clinical interventions in aging · 2025Article
- Bidirectional Relationship Between Hypoalbuminemia and Postoperative Pneumonia in Elderly Hip Fracture Patients: A Retrospective Cohort Study.Clinical interventions in aging · 2025Article
- Construction of a risk prediction model for postoperative pneumonia based on the prognostic nutritional index and analysis of related factors in patients with intracerebral hemorrhage.Frontiers in nutrition · 2025Article
- Machine Learning-Based Prediction of Postoperative Pneumonia Among Super-Aged Patients With Hip Fracture.Clinical interventions in aging · 2025Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Pneumonia is a devastating complication following geriatric hip fracture surgery, and preoperative hypoalbuminemia may be a potentially modifiable factor leading to improved outcome. This study aimed to quantify the relationship between preoperative hypoalbuminemia and postoperative pneumonia. Methods: We retrospectively reviewed the medical records of elderly patients (≥60 years) who underwent surgeries for hip fracture in a tertiary referral center between 2016 and 2020. According to the preoperative serum albumin level, they were divided into two groups: <35 g/ L and ≥35 g/ L. To reduce potential confounding, propensity score matching (PSM) in a 1:1 ratio was performed, with the caliper value set as 0.002; and further conditional logistic regression analysis was used to control the other potential confounders to determine the association strength. Results: Among 3,147 eligible patients included, PSM yielded 1,318 matched patients, with 659 in each respective group, suggesting significantly improved balance in most variables (standardized mean deviation improvement range, 20.7% to 99.1%), except for basophil count. The conditional logistic regression analysis, adjusted for PS and other intra- or post-operative variables, showed 6.18-fold (relative ratio, 6.18; 95% CI, 3.15-11.98; P<0.001) increased risk of postoperative pneumonia associated with preoperative hypoalbuminemia. Conclusion: Preoperative hypoalbuminemia was identified to be independently and highly associated with development of postoperative pneumonia in elderly patients undergoing hip fracture surgeries. However, whether the patients who had such condition may benefit from preoperative targeted nutritional support needs to be clarified by more prospective studies.
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