Evidence map›Paper›PMID 35444330›Full record

ArticleBiomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia2022

The prognosis and therapeutic management of patients hospitalized for heart failure in 2010-2020.

Otto Mayer, Jan Bruthans, Simona Bilkova, Jitka Seidlerova, Josef Jirak, Jan Filipovsky

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Article in Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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2citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Otto Mayer2nd Department of Internal Medicine, Faculty of Medicine, Charles University and University Hospital, Pilsen, Czech Republic.
Jan Bruthans2nd Department of Internal Medicine, Faculty of Medicine, Charles University and University Hospital, Pilsen, Czech Republic.
Simona Bilkova2nd Department of Internal Medicine, Faculty of Medicine, Charles University and University Hospital, Pilsen, Czech Republic.
Jitka Seidlerova2nd Department of Internal Medicine, Faculty of Medicine, Charles University and University Hospital, Pilsen, Czech Republic.
Josef JirakDepartment of Informatics, University Hospital Pilsen, Czech Republic.
Jan Filipovsky2nd Department of Internal Medicine, Faculty of Medicine, Charles University and University Hospital, Pilsen, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsWe analyzed the mortality risk and its predictors in patients hospitalized for heart failure (HF).

methodsPatients discharged from hospitalization for acute decompensation of HF in 2010-2020 and younger than 86 years were followed (n=4097). We assessed the incidence and trends of all-cause death, its main predictors, and the pharmacotherapy recommended at discharge from the hospital.

resultsThe 30 days all-cause mortality was in discharged patients 3.2%, while 1-year 20.4% and 5-years 55.4%. We observed a modest trend to decreased 1-year mortality risk over time. Any increase of year of hospitalization by one was associated with about 5% lower risk in the fully adjusted model. Regarding predictors of 1-year mortality risk, a positive association was found for age over 65, history of malignancy, and peak brain natriuretic peptide during hospitalization ≥10times higher than normal concentration. In contrast, as protective factors, we identified LDL ≥1.8 mmol/L, treatment with beta-blockers, renin-angiotensin axis blockers, statins, and implanted cardioverter in the same regression model. The ejection fraction category and primary etiology of HF (coronary artery disease vs. others) did not significantly affect the mortality risk in a fully adjusted model.

conclusionsDespite advances in cardiovascular disease management over the last two decades, the prognosis of patients hospitalized for heart failure remained highly unfavorable.

Indexed as

Heart FailureHydroxymethylglutaryl-CoA Reductase InhibitorsAngiotensinsHospitalizationHumansNatriuretic Peptide, BrainPrognosisReninStroke VolumeAngiotensinsHydroxymethylglutaryl-CoA Reductase InhibitorsNatriuretic Peptide, BrainRenincardiac decompensationhospitalizationmortality riskpharmacotherapy

Identifiers

PMID35444330

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Texttitle and abstract
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.