ArticleNature2022
Evaluating ribosomal frameshifting in CCR5 mRNA decoding.
Abstract readLetter
In one paragraph
Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- When RNA goes off script: ensuring transcript fidelity in transgene expression.The EMBO journal · 2026Review
- Feedback from the Nascent Chain Triggers Ribosomal Frameshifting and Transcript Decay.bioRxiv : the preprint server for biology · 2025Article
- The role of chikungunya virus capsid-viral RNA interactions in programmed ribosomal frameshifting.Journal of virology · 2025Article
- Programmed ribosomal frameshifting duringScience advances · 2025Article
- The dual luciferase assay does not support claims of stop codon readthrough on the AGO1 mRNA.The EMBO journal · 2025Article
- Structural switching dynamically controls the doubly pseudoknotted Rous sarcoma virus-programmed ribosomal frameshifting element.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Guidelines for minimal reporting requirements, design and interpretation of experiments involving the use of eukaryotic dual gene expression reporters (MINDR).Nature structural & molecular biology · 2025Review
- RNA elements required for the high efficiency of West Nile virus-induced ribosomal frameshifting.Nucleic acids research · 2025Article
- Ribosomal frameshifting selectively modulates the assembly, function, and pharmacological rescue of a misfolded CFTR variant.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Evolution of Virus-like Features and Intrinsically Disordered Regions in Retrotransposon-derived Mammalian Genes.Molecular biology and evolution · 2024Article
- Ribosomal Frameshifting Selectively Modulates the Assembly, Function, and Pharmacological Rescue of a Misfolded CFTR Variant.bioRxiv : the preprint server for biology · 2024Article
- A system of reporters for comparative investigation of EJC-independent and EJC-enhanced nonsense-mediated mRNA decay.Nucleic acids research · 2024Article
- Ribosomal frameshifting at normal codon repeats recodes functional chimeric proteins in human.Nucleic acids research · 2024Article
- Systematic analysis of nonprogrammed frameshift suppression inProceedings of the National Academy of Sciences of the United States of America · 2024Article
- The Deficiency of Hypusinated eIF5A Decreases the Putrescine/Spermidine Ratio and Inhibits +1 Programmed Ribosomal Frameshifting during the Translation of Ty1 Retrotransposon inInternational journal of molecular sciences · 2024Article
- Programmable modulation of ribosomal frameshifting by mRNA targeting CRISPR-Cas12a system.iScience · 2023Article
- Article
- Nontriplet feature of genetic code inProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Monitoring translation in all reading frames downstream of weak stop codons provides mechanistic insights into the impact of nucleotide and cellular contexts.Nucleic acids research · 2023Article
- Features and factors that dictate if terminating ribosomes cause or counteract nonsense-mediated mRNA decay.The Journal of biological chemistry · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Yousuf A Khan *Division of Virology, Department of Pathology, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-0201-2796
Gary Loughran *School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.
Anna-Lena SteckelbergDepartment of Biochemistry and Molecular Genetics, Denver School of Medicine, Aurora, CO, USA.
Katherine BrownDivision of Virology, Department of Pathology, University of Cambridge, Cambridge, UK.
Stephen J KinirySchool of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.
Hazel StewartDivision of Virology, Department of Pathology, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-1438-1089
Pavel V BaranovSchool of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.ORCID http://orcid.org/0000-0001-9017-0270
Jeffrey S KieftDepartment of Biochemistry and Molecular Genetics, Denver School of Medicine, Aurora, CO, USA. jeffrey.kieft@cuanschutz.edu.ORCID http://orcid.org/0000-0002-3718-1891
Andrew E FirthDivision of Virology, Department of Pathology, University of Cambridge, Cambridge, UK. aef24@cam.ac.uk.ORCID http://orcid.org/0000-0002-7986-9520
John F AtkinsSchool of Biochemistry and Cell Biology, University College Cork, Cork, Ireland. j.atkins@ucc.ie.ORCID http://orcid.org/0000-0001-7933-0165
Funding
Structure, function, and dynamics of viral RNAs and RNA-containing complexesR35GM118070 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI Jeffrey S Kieft · 2016 to 2026
$10.6MMechanisms of viral RNA maturation by co-opting cellular exonucleasesR01AI133348 · NIAID · UNIVERSITY OF COLORADO DENVER · PI KIEFT, JEFFREY S · 2017 to 2025
$4.5MNIAID NIH HHS R01 AI133348NIGMS NIH HHS R35 GM118070Wellcome Trust 106207Wellcome Trust 210692/Z/18Wellcome Trust 210692/Z/18/Z
Abstract
PubMed holds no abstract for this paper.
Indexed as
Frameshifting, RibosomalRibosomesNucleic Acid ConformationRNA, MessengerRNA, Messenger
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.