Evidence map›Paper›PMID 35444273›Full record

ArticleNature2022

Specification of CNS macrophage subsets occurs postnatally in defined niches.

Takahiro Masuda, Lukas Amann, Gianni Monaco, Roman Sankowski, Ori Staszewski, Martin Krueger, Francesca Del Gaudio, Liqun He, Neil Paterson, Elisa Nent and 20 more

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 192 papers.

0numbers the graph read from it
0cells of the map it votes in
192citing papers in PubMed
21.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

192 citing papers in PubMed, 272 citations in OpenAlex.

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  15. Macrophages in embryonic development.Nature reviews. Immunology · 2026
    Review
  16. Article
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  19. Vascular basement membrane laminins modulate functional zonation of cerebral microvessels.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Article
  20. Article

132 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

30 authors at 11 institutions in 6 countries.

Takahiro Masuda *Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany. masuda@phar.kyushu-u.ac.jp.ORCID http://orcid.org/0000-0003-3687-452X
Lukas Amann *Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0002-8363-373X
Gianni MonacoInstitute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Roman SankowskiInstitute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0001-9215-8021
Ori StaszewskiInstitute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Martin KruegerInstitute of Anatomy, University of Leipzig, Leipzig, Germany.
Francesca Del GaudioDepartment of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden.
Liqun HeDepartment of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
Neil PatersonMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.ORCID http://orcid.org/0000-0001-9563-5874
Elisa NentMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Francisco Fernández-KlettNeuropsychiatry and Laboratory of Molecular Psychiatry, Charité - Universitätsmedizin Berlin, and DZNE, Berlin, Germany.
Ayato YamasakiDepartment of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Maximilian FroschInstitute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0002-5418-0962
Maximilian FliegaufInstitute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Lance Fredrick Pahutan BoschInstitute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0002-2741-3855
Hatice UlupinarInstitute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Nora HagemeyerInstitute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Dietmar SchreinerInstitute of Neuroanatomy and Cell Biology, Hannover Medical School, Hannover, Germany.
Cayce DorrierDepartment of Neurosciences, University of California San Diego, San Diego, CA, USA.
Makoto TsudaDepartment of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.ORCID http://orcid.org/0000-0003-0585-9570
Claudia GrotheInstitute of Neuroanatomy and Cell Biology, Hannover Medical School, Hannover, Germany.
Anne JoutelInstitute of Psychiatry and Neurosciences of Paris (IPNP), Inserm, University of Paris, Paris, France.
Richard DanemanDepartment of Neurosciences, University of California San Diego, San Diego, CA, USA.ORCID http://orcid.org/0000-0002-7749-6353
Christer BetsholtzDepartment of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
Urban LendahlDepartment of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden.ORCID http://orcid.org/0000-0001-9543-8141
Klaus-Peter KnobelochInstitute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0003-1587-1944
Tim LämmermannMax Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
Josef PrillerNeuropsychiatry and Laboratory of Molecular Psychiatry, Charité - Universitätsmedizin Berlin, and DZNE, Berlin, Germany.
Katrin KierdorfInstitute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0002-9272-4780
Marco PrinzInstitute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany. marco.prinz@uniklinik-freiburg.de.ORCID http://orcid.org/0000-0002-0349-1955
University of Freiburg · DEKyushu University · JPKarolinska Institutet · SEMax Planck Institute of Immunobiology and Epigenetics · DEMedizinische Hochschule Hannover · DEUniversity of California San Diego · USUppsala University · SECharité - Universitätsmedizin Berlin · DEInserm · FRLeipzig University · DEUK Dementia Research Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All tissue-resident macrophages of the central nervous system (CNS)-including parenchymal microglia, as well as CNS-associated macrophages (CAMs

Indexed as

Cell LineageCentral Nervous SystemMacrophagesFemaleHumansImmunity, InnateMicrogliaPregnancyYolk Sac

Identifiers

PMID35444273
OpenAlexW4224295368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.