Evidence map›Paper›PMID 35443961›Full record

ArticleBMJ open2022

Scalable psychological interventions for Syrian refugees in Europe and the Middle East: STRENGTHS study protocol for a prospective individual participant data meta-analysis.

Anne M de Graaff, Pim Cuijpers, Ceren Acarturk, Aemal Akhtar, Mhd Salem Alkneme, May Aoun, Manar Awwad, Ahmad Y Bawaneh, Felicity L Brown, Richard Bryant and 33 more

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

43 authors at 12 institutions in 7 countries.

Anne M de GraaffDepartment of Clinical, Neuro- and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands a.m.de.graaff@vu.nl.ORCID 0000-0001-6686-4432
Pim CuijpersDepartment of Clinical, Neuro- and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0001-5497-2743
Ceren AcarturkDepartment of Psychology, Koç University, Istanbul, Turkey.ORCID 0000-0001-7093-1554
Aemal AkhtarSchool of Psychology, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-8510-3636
Mhd Salem AlknemeDivision of Clinical-Psychological Intervention, Department of Education and Psychology, Freie Universitat Berlin, Berlin, Germany.ORCID 0000-0002-4593-6705
May AounResearch and Development Department, War Child, Amsterdam, The Netherlands.
Manar AwwadTechnical Unit, International Medical Corps, London, UK.
Ahmad Y BawanehTechnical Unit, International Medical Corps, London, UK.
Felicity L BrownResearch and Development Department, War Child, Amsterdam, The Netherlands.ORCID 0000-0001-6800-1657
Richard BryantSchool of Psychology, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-9607-819X
Sebastian BurchertDivision of Clinical-Psychological Intervention, Department of Education and Psychology, Freie Universitat Berlin, Berlin, Germany.ORCID 0000-0003-3126-5485
Kenneth CarswellDepartment of Mental Health and Substance Abuse, World Health Organization, Geneve, Switzerland.ORCID 0000-0001-5344-5802
Annelieke DrogendijkARQ International, ARQ National Psychotrauma Centre, Amsterdam, The Netherlands.
Michelle EngelsInternational Federation of Red Cross and Red Crescent Societies Reference Centre for Psychosocial Support, Copenhagen, Denmark.ORCID 0000-0002-3782-1609
Daniela C FuhrDepartment of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0001-9020-4629
Pernille HansenInternational Federation of Red Cross and Red Crescent Societies Reference Centre for Psychosocial Support, Copenhagen, Denmark.ORCID 0000-0002-4782-458X
Edith van 't HofDepartment of Mental Health and Substance Abuse, World Health Organization, Geneve, Switzerland.ORCID 0000-0002-5856-3573
Luana GiardinelliTechnical Unit, International Medical Corps, London, UK.
Mahmoud HemmoDepartment of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, Zurich, Switzerland.ORCID 0000-0002-2958-0702
Jonas M HesslingDivision of Clinical-Psychological Intervention, Department of Education and Psychology, Freie Universitat Berlin, Berlin, Germany.
Zeynep IlkkursunDepartment of Psychology, Koç University, Istanbul, Turkey.ORCID 0000-0001-6691-1809
Mark J D JordansResearch and Development Department, War Child, Amsterdam, The Netherlands.ORCID 0000-0001-5925-8039
Nikolai KiselevDepartment of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, Zurich, Switzerland.ORCID 0000-0003-0617-0353
Christine KnaevelsrudDivision of Clinical-Psychological Intervention, Department of Education and Psychology, Freie Universitat Berlin, Berlin, Germany.ORCID 0000-0003-1342-7006
Gülsah KurtDepartment of Psychology, Koç University, Istanbul, Turkey.
Saara MartinmäkiARQ International, ARQ National Psychotrauma Centre, Amsterdam, The Netherlands.ORCID 0000-0003-0230-4641
David McDaidCare Policy and Evaluation Centre, Department of Health Policy, The London School of Economics and Political Science, London, UK.ORCID 0000-0003-0744-2664
Naser MorinaDepartment of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, Zurich, Switzerland.ORCID 0000-0002-6470-4408
Hadeel NaserTechnical Unit, International Medical Corps, London, UK.
A-La ParkCare Policy and Evaluation Centre, Department of Health Policy, The London School of Economics and Political Science, London, UK.ORCID 0000-0002-4704-4874
Monique C PfaltzDepartment of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, Zurich, Switzerland.ORCID 0000-0002-7762-6226
Bayard RobertsDepartment of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK.
Matthis SchickDepartment of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, Zurich, Switzerland.
Ulrich SchnyderDepartment of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, Zurich, Switzerland.ORCID 0000-0003-3556-7990
Julia SpaaijDepartment of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, Zurich, Switzerland.
Frederik SteenResearch and Development Department, War Child, Amsterdam, The Netherlands.
Karine TahaResearch and Development Department, War Child, Amsterdam, The Netherlands.
Ersin UygunTrauma and Disaster Mental Health Master Programme, Istanbul Bilgi University, Istanbul, İstanbul, Turkey.
Peter VentevogelPublic Health, United Nations High Commissioner for Refugees, Geneva, Switzerland.ORCID 0000-0002-3567-8861
Claire WhitneyTechnical Unit, International Medical Corps, London, UK.ORCID 0000-0002-1100-5363
Anke B WitteveenDepartment of Clinical, Neuro- and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-9636-7522
Marit SijbrandijDepartment of Clinical, Neuro- and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0001-5430-9810
STRENGTHS consortium
University Hospital of Zurich · CHWar Child · NLFreie Universität Berlin · DEVrije Universiteit Amsterdam · NLKoç University · TRArq Psychotrauma Expert Group · NLLondon School of Economics and Political Science · GBLondon School of Hygiene & Tropical Medicine · GBUNSW Sydney · AUWorld Health Organization · CHIstanbul Bilgi University · TROffice of the United Nations High Commissioner for Refugees · CH

Funding

World Health Organization 001
6 · The paper itself

Abstract

introductionThe World Health Organization's (WHO) scalable psychological interventions, such as Problem Management Plus (PM+) and Step-by-Step (SbS) are designed to be cost-effective non-specialist delivered interventions to reduce symptoms of common mental disorders, such as anxiety, depression and post-traumatic stress disorder (PTSD). The STRENGTHS consortium aims to evaluate the effectiveness, cost-effectiveness and implementation of the individual format of PM+ and its group version (gPM+), as well as of the digital SbS intervention among Syrian refugees in seven countries in Europe and the Middle East. This is a study protocol for a prospective individual participant data (IPD) meta-analysis to evaluate (1) overall effectiveness and cost-effectiveness and (2) treatment moderators of PM+, gPM+ and SbS with Syrian refugees. METHODS AND ANALYSIS: Five pilot randomised controlled trials (RCTs) and seven fully powered RCTs conducted within STRENGTHS will be combined into one IPD meta-analytic dataset. The RCTs include Syrian refugees of 18 years and above with elevated psychological distress (Kessler Psychological Distress Scale (K10>15)) and impaired daily functioning (WHO Disability Assessment Schedule 2.0 (WHODAS 2.0>16)). Participants are randomised into the intervention or care as usual control group, and complete follow-up assessments at 1-week, 3-month and 12-month follow-up. Primary outcomes are symptoms of depression and anxiety (25-item Hopkins Symptom Checklist). Secondary outcomes include daily functioning (WHODAS 2.0), PTSD symptoms (PTSD Checklist for DSM-5) and self-identified problems (PSYCHLOPS). We will conduct a one-stage IPD meta-analysis using linear mixed models. Quality of evidence will be assessed using the GRADE approach, and the economic evaluation approach will be assessed using the CHEC-list. ETHICS AND DISSEMINATION: Local ethical approval has been obtained for each RCT. This IPD meta-analysis does not require ethical approval. The results of this study will be published in international peer-reviewed journals.

Indexed as

RefugeesStress Disorders, Post-TraumaticHumansMeta-Analysis as TopicMiddle EastPsychosocial InterventionRandomized Controlled Trials as TopicSyriaAnxiety disordersDepression & mood disordersMENTAL HEALTH

Identifiers

PMID35443961
PMCPMC9021771
OpenAlexW4224298240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.