Evidence map›Paper›PMID 35443838›Full record

ArticleAnnals of medicine2022

Prolonged duration of epidural labour analgesia decreases the success rate of epidural anaesthesia for caesarean section.

Zhang Jian, Ran Longqing, Wei Dayuan, Jia Fei, Liu Bo, Zhang Gang, Zhu Siying, Gao Yan

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07007650 (Effects of Different Concentrations of Ropivacaine on Prolonged Labor Analgesia), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07007650 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Different Concentrations of Ropivacaine on Prolonged Labor Analgesia

TypeinterventionalSponsorChengdu Jinjiang Maternity and Child Health HospitalRan2025 to 2025Enrolled100ConditionsLabor Analgesia, Prolonged, Ropivacaine, ConcentrationArmsHigh-concentration Ropivacaine, Low concentration ropivacaine group
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Zhang JianSichuan Provincial Maternity and Child Health Care Hospital (Women's and Children's Hospital Affiliated of Chengdu Medical College), Chengdu.
Ran LongqingChengdu Women's and Children's Central Hospital (School of Medicine, University of Electronic Science and Technology of China), Chengdu.
Wei DayuanChengdu Medical College, Chengdu.
Jia FeiJinjiang Maternity and Child Health Hospital, Chengdu.
Liu BoJinjiang Maternity and Child Health Hospital, Chengdu.
Zhang GangSichuan Provincial Maternity and Child Health Care Hospital (Women's and Children's Hospital Affiliated of Chengdu Medical College), Chengdu.
Zhu SiyingSichuan Provincial Maternity and Child Health Care Hospital (Women's and Children's Hospital Affiliated of Chengdu Medical College), Chengdu.
Gao YanSichuan Provincial Maternity and Child Health Care Hospital (Women's and Children's Hospital Affiliated of Chengdu Medical College), Chengdu.
Chengdu Medical College · CNJingzhou Maternal and Child Health Hospital · CNChengdu Women's and Children's Central Hospital · CNMaternal and Child Health Hospital of Sichuan Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo summarise the process of conversion of epidural labour analgesia to anaesthesia for caesarean delivery and explore the relationship between duration of labour analgesia and conversion.

methodsParturients who underwent conversion from epidural labour analgesia to anaesthesia for caesarean delivery between May 2019 and April 2020 at the Chengdu Women's and Children's Central Hospital, Sichuan Maternal and Child Health Hospital, and Jinjiang District Maternal and Child Health Hospital were selected. If the position of the epidural catheter was correct and the effect was good, patients were converted to epidural surgical anaesthesia. If epidural labour analgesia was ineffective, spinal anaesthesia (SA) was administered immediately. For category-1 emergency caesarean sections, general anaesthesia (GA) was administered.

resultsA total of 1084 parturients underwent conversion. Of these, 19 (1.9%) received GA due to the initiation of category-1 emergency caesarean section. 704 (64.9%) were converted to epidural surgical anaesthesia, 2 (0.2%) had failed conversions and were administered GA before delivery, and 357 (32.9%) were converted to SA. Logistic regression analysis showed that prolonged duration of epidural labour analgesia ([Crude odds ratio (OR)=1.065; 95% confidence interval (CI), 1.037-1.094;

conclusionProlonged duration of epidural labour analgesia increases the possibility of having an invalid epidural catheter, resulting in an increased risk of conversion failure from epidural labour analgesia to epidural surgical anaesthesia. Further, this risk is higher when the time exceeds 8 h. KEY MESSAGESProlonged duration of epidural labour analgesia > 8 h is associated with conversion failure.If it is impossible to judge whether the conversion is successful immediately, spinal anaesthesia should be administered to minimise complications.

Indexed as

Analgesia, EpiduralAnalgesia, ObstetricalAnesthesia, EpiduralLabor, ObstetricCesarean SectionChildFemaleHumansPregnancycaesarean sectionduration of epidural labour analgesiaepidural anaesthesiaLabour analgesiaspinal anaesthesia

Identifiers

PMID35443838
PMCPMC9891221
OpenAlexW4224215142

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.