Evidence map›Paper›PMID 35443622›Full record

ArticleBMC pregnancy and childbirth2022

Preconception leisure-time physical activity and family history of stroke and myocardial infarction associate with preterm delivery: findings from a Norwegian cohort.

Tone Engen, Katrine Mari Owe, Julie Horn, Gerhard Sulo, Øyvind Erik Næss, Petur Benedikt Juliusson, Nils-Halvdan Morken, Grace Margrethe Egeland

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Tone EngenDepartment of Health and Caring Sciences, Western Norway University of Applied Sciences, Inndalsveien 28, 5063, Bergen, Norway.
Katrine Mari OweNorwegian Research Centre for Women's Health, Oslo University Hospital HF, Riks Hospital, Oslo, Norway and Division of Mental and Physical Health, Norwegian Institute of Public health, Oslo, Norway.
Julie HornDepartment of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway & Department of Obstetrics and Gynecology, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger Hospital, Kirkegata 2, N-7600, Levanger, Norway.
Gerhard SuloCentre for Disease Burden, Division of Mental and Physical Health, Norwegian Institute of Public Health, Bergen, Norway; & Oral Health Centre of Expertise in Western Norway-Vestland, Bergen, Norway.
Øyvind Erik NæssDivision of Mental and Physical Health, Norwegian Institute of Public Health & University of Oslo, Oslo, Norway &Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway.
Petur Benedikt JuliussonHealth Registries Research and Development, Division of Health Data and Digitalization, Norwegian Institute of Public Health, Bergen, Post Box 973 Sentrum, 5808, Bergen, Norway.
Nils-Halvdan MorkenDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Grace Margrethe EgelandHealth Registries Research and Development, Division of Health Data and Digitalization, Norwegian Institute of Public Health, Bergen, Post Box 973 Sentrum, 5808, Bergen, Norway. g.egeland@uib.no.
Norwegian Institute of Public Health · NOHaukeland University Hospital · NONorwegian University of Science and Technology · NOOslo University Hospital · NOUniversity of Oslo · NOWestern Norway University of Applied Sciences · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreterm birth poses short and long-term health consequences for mothers and offspring including cardiovascular disease sequelae. However, studies evaluating preexisting family history of cardiovascular disease and risk factors, such as physical activity, as they relate prospectively to risk of delivering preterm are lacking.

objectivesTo evaluate whether preconception past-year weekly leisure-time physical activity or a family history of stroke or of myocardical infarction prior to age 60 years in first degree relatives associated, prospectively, with preterm delivery.

designCohort study. Baseline data from Cohort Norway (1994-2003) health surveys were linked to the Medical Birth Registry of Norway for identification of all subsequent births (1994-2012). Logistic regression models provided odds ratios (OR) and 95% confidence intervals (CI) for preterm delivery (< 37 weeks gestation); multinomial logistic regression provided OR for early preterm (< 34 weeks) and late preterm (34 through to end of 36 weeks gestation) relative to term deliveries.

resultsMean (SD) length of time from baseline health survey participation to delivery was 5.6 (3.5) years. A family history of stroke associated with a 62% greater risk for late preterm deliveries (OR 1.62; CI 1.07-2.47), while a family history of myocardial infarction associated with a 66% greater risk of early preterm deliveries (OR 1.66; CI 1.11-2.49). Sensitivity analyses, removing pregnancies complicated by hypertensive disorders of pregnancy, diabetes mellitus, and stillbirth deliveries, gave similar results. Preconception vigorous physical activity of three or more hours relative to less than 1 h per week associated with increased risk of early preterm delivery (OR 1.52; 95% CI 1.01-2.30), but not late or total preterm deliveries. Light physical activity of three or more hours per week relative to less activity prior to pregnancy was not associated with early, late, or total preterm deliveries.

conclusionsResults suggest that family history of cardiovascular disease may help identify women at risk for preterm delivery. Further, research is needed regarding preconception and very early pregnancy vigorous physical activity and associated risks.

Indexed as

Myocardial InfarctionPremature BirthStrokeCohort StudiesExerciseFemaleHumansInfant, NewbornLeisure ActivitiesMiddle AgedPregnancyRisk FactorsCardiovascular diseaseCohort studyLeisure time physical activityPregnancyPreterm birthwomen’s health

Identifiers

PMID35443622
PMCPMC9019953
OpenAlexW4224235082

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.