Evidence map›Paper›PMID 35443565›Full record

ArticleHaematologica2022

Hemostatic and protein C pathway dysfunction in the pathogenesis of experimental cerebral malaria.

Niamh O'Regan, Kristina Gegenbauer, Eimear M Gleeson, Kenji Fukudome, Jamie M O'Sullivan, Clive Drakeford, Niall Dalton, Alain Chion, Teresa M Brophy, Owen P Smith and 2 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Niamh O'ReganHaemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James's Hospital, Trinity College Dublin.
Kristina GegenbauerHaemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James's Hospital, Trinity College Dublin.
Eimear M GleesonHaemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James's Hospital, Trinity College Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital, Crumlin.
Kenji FukudomeDepartment of Life Science, Saga University Organization for General Education, Saga.
Jamie M O'SullivanHaemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James's Hospital, Trinity College Dublin, Ireland; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin 2.
Clive DrakefordHaemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James's Hospital, Trinity College Dublin.
Niall DaltonHaemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James's Hospital, Trinity College Dublin.
Alain ChionHaemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James's Hospital, Trinity College Dublin, Ireland; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin 2.
Teresa M BrophyHaemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James's Hospital, Trinity College Dublin.
Owen P SmithNational Children's Research Centre, Our Lady's Children's Hospital, Crumlin, Dublin; Haematology Dept, Our Lady's Children's Hospital, Dublin.
Roger J S PrestonNational Children's Research Centre, Our Lady's Children's Hospital, Crumlin, Dublin; National Coagulation Centre, St James's Hospital, Dublin.
James S O'DonnellNational Children's Research Centre, Our Lady's Children's Hospital, Crumlin, Dublin; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland; National Coagulation Centre, St James's Hospital, Dublin. jamesodonnell@rcsi.ie.
St. James's Hospital · IETrinity College Dublin · IEInstitute of Molecular Medicine · INNational Children’s Research Centre · IEOur Lady's Hospital · IESaga University · JP

Funding

Zimmerman Program for the Molecular and Clinical Biology of VWDP01HL081588 · NHLBI · VERSITI WISCONSIN, INC. · PI MONTGOMERY, ROBERT R · 2005 to 2016
$19.3M
NHLBI NIH HHS P01 HL081588
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HemostaticsMalaria, CerebralAnimalsBlood Coagulation TestsDisease Models, AnimalHumansPlasmodium bergheiProtein CHemostaticsProtein C

Identifiers

PMID35443565
PMCPMC9335116
OpenAlexW4224295342

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.