ArticleCell reports2022
Optogenetic activation of the inhibitory nigro-collicular circuit evokes contralateral orienting movements in mice.
Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Behavioral correlates of Purkinje cell ensemble covariance.Nature communications · 2026Article
- Correlates of head-fixed directional forelimb movements in mouse superior colliculus and substantia nigra pars reticulata.Neuroscience · 2026Article
- Basal ganglia output dynamically controls skilled forelimb kinematics in real time.bioRxiv : the preprint server for biology · 2026Article
- Ascending and descending motor pathways converge in the centrolateral nucleus of the thalamus.Research square · 2026Article
- Treadmill exercise improves motor deficits and partially normalizes electrophysiological properties of substantia nigra pars reticulata PV-lineage neurons in 6-OHDA-lesioned mice.Frontiers in physiology · 2026Article
- Superior colliculus projections drive dopamine neuron activity and movement but not value.bioRxiv : the preprint server for biology · 2025Article
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- A Novel Method for the Locomotion Control of a Rat Robot via the Electrical Stimulation of the Ventral Tegmental Area and Nigrostriatal Pathway.Brain sciences · 2025Article
- Stimulus selection enhances value-modulated somatosensory processing in the superior colliculus.PLoS biology · 2025Article
- Basal ganglia-spinal cord pathway that commands locomotor gait asymmetries in mice.Nature neuroscience · 2024Article
- Neural mechanisms for the localization of unexpected external motion.Nature communications · 2023Article
- Pathway-specific inputs to the superior colliculus support flexible responses to visual threat.Science advances · 2023Article
- The Superior Colliculus: Cell Types, Connectivity, and Behavior.Neuroscience bulletin · 2022Review
- Functional Organisation of the Mouse Superior Colliculus.Frontiers in neural circuits · 2022Review
- Neurons gating behavior-developmental, molecular and functional features of neurons in the Substantia Nigra pars reticulata.Frontiers in neuroscience · 2022Article
- Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements.Communications biology · 2021Article
- Superior Colliculus Controls the Activity of the Rostromedial Tegmental Nuclei in an Asymmetrical Manner.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Unraveling circuits of visual perception and cognition through the superior colliculus.Neuron · 2021Review
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Authors and funding
2 authors.
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Abstract
We report that increasing inhibition from the basal ganglia (BG) to the superior colliculus (SC) through the substantia nigra pars reticulata (nigra) using in vivo optogenetic activation of GABAergic terminals in mice produces contralateral orienting movements. These movements are unexpected because decreases, and not increases, in nigral activity are generally associated with the initiation of orienting movements. We found that, in slice recordings, the same optogenetic stimulation of nigral terminals producing movements in vivo evokes post-inhibitory rebound depolarization followed by Na
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