ArticleCell reports2022
A dual-function phage regulator controls the response of cohabiting phage elements via regulation of the bacterial SOS response.
Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- Characterization of a novel phage-plasmid vB_EcoM_ED targeting multidrug-resistant Escherichia coli isolates.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- The microbiota of wooden cheese-ripening boards is a rich source of antimicrobial-producing bacteria againstMicrobiology spectrum · 2026Article
- Lifestyle shapes genome architecture and codon usage bias inFrontiers in microbiology · 2026Article
- Article
- Insights into the dynamics and evolution of Rummeliibacillus stabekisii prophages in extreme environments: from Antarctic soil to spacecraft floors.Extremophiles : life under extreme conditions · 2024Article
- A prophage competition element protects Salmonella from lysis.Cell host & microbe · 2024Article
- Experimental evolution under different nutritional conditions changes the genomic architecture and virulence of Acinetobacter baumannii.Communications biology · 2024Article
- Specialized Listeria monocytogenes produce tailocins to provide a population-level competitive growth advantage.Nature microbiology · 2024Article
- Isolation and Characterization of Six NovelPHAGE (New Rochelle, N.Y.) · 2024Article
- Genome Analysis of Epsilon CrAss-like Phages.Viruses · 2024Article
- Identification and genomic analysis of temperateMicrobiology spectrum · 2023Article
- Chance Favors the Prepared Genomes: Horizontal Transfer Shapes the Emergence of Antibiotic Resistance Mutations in Core Genes.Molecular biology and evolution · 2023Article
- Comprehensive Characterization of aPharmaceuticals (Basel, Switzerland) · 2023Article
- Induction mechanisms and strategies underlying interprophage competition during polylysogeny.PLoS pathogens · 2023Article
- Disarm The Bacteria: What Temperate Phages Can Do.Current issues in molecular biology · 2023Review
- A small bacteriophage protein determines the hierarchy over co-residential jumbo phage in Bacillus thuringiensis serovar israelensis.Communications biology · 2022Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Listeria monocytogenes strain 10403S harbors two phage elements in its chromosome; one produces infective virions and the other tailocins. It was previously demonstrated that induction of the two elements is coordinated, as they are regulated by the same anti-repressor. In this study, we identified AriS as another phage regulator that controls the two elements, bearing the capacity to inhibit their lytic induction under SOS conditions. AriS is a two-domain protein that possesses two distinct activities, one regulating the genes of its encoding phage and the other downregulating the bacterial SOS response. While the first activity associates with the AriS N-terminal AntA/AntB domain, the second associates with its C-terminal ANT/KilAC domain. The ANT/KilAC domain is conserved in many AriS-like proteins of listerial and non-listerial prophages, suggesting that temperate phages acquired such dual-function regulators to align their response with the other phage elements that cohabit the genome.
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