Evidence map›Paper›PMID 35442864›Full record

ArticleAmerican journal of respiratory and critical care medicine2022

Physiology Is Vital to Precision Medicine in Acute Respiratory Distress Syndrome and Sepsis.

Ewan C Goligher, Irene Telias, Sarina K Sahetya, Elias Baedorf-Kassis, Bhakti K Patel, Nadir Yehya, Jonathan A Silversides, Niall D Ferguson, Laurent J Brochard, Patrick R Lawler and 2 more

Open access · hybridAbstract readEditorial
In one paragraph

Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Beyond vasodilation: reframing inhaled nitric oxide as a precision therapy.American journal of respiratory and critical care medicine · 2026
    Article
  2. Article
  3. Article
  4. Observational
  5. Observational
  6. Article
  7. Article
  8. Toward a Broader Characterization of Macro- and Microcirculatory Uncoupling in Cardiogenic Shock.American journal of respiratory and critical care medicine · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 4 countries.

Ewan C GoligherInterdepartmental Division of Critical Care Medicine University of Toronto Toronto, Ontario, Canada.ORCID 0000-0002-0990-6701
Irene TeliasInterdepartmental Division of Critical Care Medicine University of Toronto Toronto, Ontario, Canada.
Sarina K SahetyaSchool of Medicine Johns Hopkins University Baltimore, Maryland.ORCID 0000-0003-2127-3609
Elias Baedorf-KassisDivision of Pulmonary and Critical Care Harvard Medical School Boston, Massachusetts.
Bhakti K PatelDepartment of Medicine University of Chicago Chicago, Illinois.
Nadir YehyaDepartment of Anesthesiology and Critical Care Medicine Children's Hospital of Philadelphia Philadelphia, Pennsylvania.
Jonathan A SilversidesWellcome-Wolfson Institute for Experimental Medicine Queen's University Belfast Belfast, United Kingdom.
Niall D FergusonInterdepartmental Division of Critical Care Medicine University of Toronto Toronto, Ontario, Canada.
Laurent J BrochardInterdepartmental Division of Critical Care Medicine University of Toronto Toronto, Ontario, Canada.
Patrick R LawlerInterdepartmental Division of Critical Care Medicine University of Toronto Toronto, Ontario, Canada.
Ryan ZarychanskiDepartment of Medical Oncology and Hematology CancerCare Manitoba Winnipeg, Manitoba, Canada.
Arthur S SlutskyInterdepartmental Division of Critical Care Medicine University of Toronto Toronto, Ontario, Canada.
University Health Network · CAUniversity of Toronto · CACancerCare Manitoba · CAChildren's Hospital of Philadelphia · USHarvard University · USJohns Hopkins University · USQueen's University Belfast · GBUniversity of Chicago · US

Funding

Driving Pressure as a Target for Lung-Protective VentilationK23HL155507 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI SAHETYA, SARINA · 2021 to 2025
$885k
Early Mobilization: Operationalizing Big Data & Implementation Science to Lead Expansion to ICUs (E-MOBILE-ICU)K23HL148387 · NHLBI · UNIVERSITY OF CHICAGO · PI PATEL, BHAKTI KIRAN · 2020 to 2024
$812k
CIHR Early Career Investigator Award (AR7-162822)NHLBI NIH HHS K23 HL148387NHLBI NIH HHS K23 HL155507
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Respiratory Distress SyndromeSepsisHumansPrecision Medicine

Identifiers

PMID35442864
PMCPMC9954327
OpenAlexW4224284075

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.