Evidence map›Paper›PMID 35442800›Full record

ArticleMetabolic syndrome and related disorders2022

The Effect of Diabetes-Associated Variation in

Jon D Adams, Aoife M Egan, Marcello C Laurenti, Daniel Schembri Wismayer, Kent R Bailey, Claudio Cobelli, Chiara Dalla Man, Adrian Vella

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolic syndrome and related disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Abnormal Glucagon Secretion Contributes to a Longitudinal Decline in Glucose Tolerance.The Journal of clinical endocrinology and metabolism · 2025
    Observational
  3. Article
  4. Diabetes-associated Genetic Variation inJournal of the Endocrine Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Jon D AdamsDivision of Endocrinology, Diabetes and Metabolism, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Aoife M EganDivision of Endocrinology, Diabetes and Metabolism, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Marcello C LaurentiDivision of Endocrinology, Diabetes and Metabolism, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Daniel Schembri WismayerDivision of Endocrinology, Diabetes and Metabolism, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Kent R BaileyDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA.
Claudio CobelliDepartment of Woman and Child's Health, University of Padova, Padova, Italy.
Chiara Dalla ManDepartment of Information Engineering, University of Padova, Padova, Italy.
Adrian VellaDivision of Endocrinology, Diabetes and Metabolism, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.ORCID 0000-0001-6493-7837
Mayo Clinic · USUniversity of Padua · IT

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
The regulation of fasting glucose metabolism in people with and without prediabetesR01DK078646 · NIDDK · MAYO CLINIC ROCHESTER · PI Adrian Vella · 2007 to 2026
$8.7M
Glucagon suppression and diabetes-associated variation in TCF7L2R01DK116231 · NIDDK · MAYO CLINIC ROCHESTER · PI Adrian Vella · 2017 to 2026
$5.4M
The effect of endogenous GLP-1 secretion on islet function in vivoR01DK126206 · NIDDK · MAYO CLINIC ROCHESTER · PI Adrian Vella · 2020 to 2026
$4.0M
NIDDK NIH HHS R01 DK078646NIDDK NIH HHS R01 DK116231NIDDK NIH HHS R01 DK126206
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, Type 2GlucagonTranscription Factor 7-Like 2 ProteinBlood GlucoseGlucoseHumansInsulinPostprandial PeriodBlood GlucoseGlucagonGlucoseInsulinTCF7L2 protein, humanTranscription Factor 7-Like 2 Proteinendogenous glucose productionmetabolismTCF7L2α cell functionβ cell function

Identifiers

PMID35442800
PMCPMC9419949
OpenAlexW4224214058

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.