Evidence map›Paper›PMID 35442685›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2022

Rational Mitomycin Nanocarriers Based on Hydrophobically Functionalized Polyelectrolytes and Poly(lactide-

Łukasz Lamch, Kazimiera A Wilk, Imre Dékány, Ágota Deák, Viktória Hornok, László Janovák

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 15 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Łukasz LamchDepartment of Engineering and Technology of Chemical Processes, Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, Wrocław 50-370, Poland.ORCID 0000-0002-0332-7119
Kazimiera A WilkDepartment of Engineering and Technology of Chemical Processes, Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, Wrocław 50-370, Poland.ORCID 0000-0002-2020-1761
Imre DékányDepartment of Physical Chemistry and Materials Science, University of Szeged, Rerrich Béla tér 1, Szeged H-6720, Hungary.
Ágota DeákDepartment of Physical Chemistry and Materials Science, University of Szeged, Rerrich Béla tér 1, Szeged H-6720, Hungary.
Viktória HornokDepartment of Physical Chemistry and Materials Science, University of Szeged, Rerrich Béla tér 1, Szeged H-6720, Hungary.ORCID 0000-0001-9933-7604
László JanovákDepartment of Physical Chemistry and Materials Science, University of Szeged, Rerrich Béla tér 1, Szeged H-6720, Hungary.ORCID 0000-0002-2066-319X
University of Szeged · HUWrocław University of Science and Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Encapsulation of hydrophilic and amphiphilic drugs in appropriate colloidal carrier systems for sustained release is an emerging problem. In general, hydrophobic bioactive substances tend to accumulate in water-immiscible polymeric domains, and the release process is controlled by their low aqueous solubility and limited diffusion from the nanocarrier matrix. Conversely, hydrophilic/amphiphilic drugs are typically water-soluble and insoluble in numerous polymers. Therefore, a core-shell approach─nanocarriers comprising an internal core and external shell microenvironments of different properties─can be exploited for hydrophilic/amphiphilic drugs. To produce colloidally stable poly(lactic-

Indexed as

MitomycinNanoparticlesDelayed-Action PreparationsDrug CarriersPolyelectrolytesPolyglactin 910WaterDelayed-Action PreparationsDrug CarriersMitomycinPolyelectrolytesPolyglactin 910Water

Identifiers

PMID35442685
PMCPMC9097536
OpenAlexW4224266890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.