Evidence map›Paper›PMID 35442642›Full record

ArticleBioconjugate chemistry2022

Pretargeted PET Imaging with a TCO-Conjugated Anti-CD44v6 Chimeric mAb U36 and [

Dave Lumen, Danielle Vugts, Marion Chomet, Surachet Imlimthan, Mirkka Sarparanta, Ricardo Vos, Maxime Schreurs, Mariska Verlaan, Pauline A Lang, Eero Hippeläinen and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Bioconjugate chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Head-to-Head Comparison of theMolecular pharmaceutics · 2025
    Article
  7. Molecular Imaging of Cancer Stem Cells and Their Role in Therapy Resistance.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Review
  8. [RSC chemical biology · 2024
    Article
  9. Review
  10. Toward OptimizedPharmaceutics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Dave LumenDepartment of Chemistry, Radiochemistry, University of Helsinki, FI-00014 Helsinki, Finland.
Danielle VugtsAmsterdam UMC, Vrije Universiteit Amsterdam, Radiology & Nuclear Medicine, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0001-7068-8152
Marion ChometAmsterdam UMC, Vrije Universiteit Amsterdam, Radiology & Nuclear Medicine, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0001-9632-4875
Surachet ImlimthanDepartment of Chemistry, Radiochemistry, University of Helsinki, FI-00014 Helsinki, Finland.ORCID 0000-0003-2520-2146
Mirkka SarparantaDepartment of Chemistry, Radiochemistry, University of Helsinki, FI-00014 Helsinki, Finland.ORCID 0000-0002-2956-4366
Ricardo VosAmsterdam UMC, Vrije Universiteit Amsterdam, Radiology & Nuclear Medicine, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Maxime SchreursAmsterdam UMC, Vrije Universiteit Amsterdam, Radiology & Nuclear Medicine, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Mariska VerlaanAmsterdam UMC, Vrije Universiteit Amsterdam, Radiology & Nuclear Medicine, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Pauline A LangDepartment of Chemistry, Radiochemistry, University of Helsinki, FI-00014 Helsinki, Finland.ORCID 0000-0003-3187-1469
Eero HippeläinenHUS Medical Imaging Center, Clinical Physiology and Nuclear Medicine, University of Helsinki and Helsinki University Hospital, 00029 HUS Helsinki, Finland.
Wissam BeainoAmsterdam UMC, Vrije Universiteit Amsterdam, Radiology & Nuclear Medicine, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Albert D WindhorstAmsterdam UMC, Vrije Universiteit Amsterdam, Radiology & Nuclear Medicine, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0002-1250-7656
Anu J AiraksinenDepartment of Chemistry, Radiochemistry, University of Helsinki, FI-00014 Helsinki, Finland.ORCID 0000-0002-5943-3105
Amsterdam University Medical Centers · NLUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent advances in the production of engineered antibodies have facilitated the development and application of tailored, target-specific antibodies. Positron emission tomography (PET) of these antibody-based drug candidates can help to better understand their

Indexed as

Head and Neck NeoplasmsPositron-Emission TomographyAntibodies, MonoclonalCell Line, TumorHumansSquamous Cell Carcinoma of Head and NeckZirconiumAntibodies, MonoclonalZirconium

Identifiers

PMID35442642
PMCPMC9121349
OpenAlexW4224242800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.