Evidence map›Paper›PMID 35442170›Full record

ArticleAmerican journal of respiratory cell and molecular biology2022

Cytidine 5'-Diphosphocholine Corrects Alveolar Type II Cell Mitochondrial Dysfunction in Influenza-infected Mice.

Lauren M Doolittle, Katherine Binzel, Katherine E Nolan, Kelsey Craig, Lucia E Rosas, Matthew C Bernier, Lisa M Joseph, Parker S Woods, Michael V Knopp, Ian C Davis

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Human Airway Basal Cells Undergo Reversible Squamous Differentiation and Reshape Innate Immunity.American journal of respiratory cell and molecular biology · 2023
    Article
  8. Review
  9. Improving Mitochondrial Function in Viral Infection: Targeting Cellular Metabolism.American journal of respiratory cell and molecular biology · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Lauren M DoolittleDepartment of Veterinary Biosciences.
Katherine BinzelWright Center of Innovation in Biomedical Imaging, and.
Katherine E NolanDepartment of Veterinary Biosciences.
Kelsey CraigDepartment of Veterinary Biosciences.
Lucia E RosasDepartment of Veterinary Biosciences.
Matthew C BernierCampus Chemical Instrument Center Mass Spectrometry and Proteomics Facility, the Ohio State University, Columbus, Ohio.
Lisa M JosephDepartment of Veterinary Biosciences.
Parker S WoodsDepartment of Veterinary Biosciences.
Michael V KnoppWright Center of Innovation in Biomedical Imaging, and.
Ian C DavisDepartment of Veterinary Biosciences.
The Ohio State University · US

Funding

Role of alterations in the ATII cell lipidome in influenza pathogenesisR01HL137090 · NHLBI · OHIO STATE UNIVERSITY · PI DAVIS, IAN CHRISTOPHER · 2017 to 2020
$2.5M
NHLBI NIH HHS R01 HL137090NHLBI NIH HHS R01-HL137090
6 · The paper itself

Abstract

Development of acute respiratory distress syndrome (ARDS) in influenza A virus (IAV)-infected mice is associated with inhibition of ATII (alveolar type II) epithelial cell

Indexed as

Influenza A virusInfluenza A Virus, H1N1 SubtypeInfluenza, HumanRespiratory Distress SyndromeAnimalsCardiolipinsCytidine Diphosphate CholineFemaleHumansMaleMiceMice, Inbred C57BLMitochondriaPhosphatidylcholinesCardiolipinsCytidine Diphosphate CholinePhosphatidylcholinescardiolipinglycolysisoxidative phosphorylationphospholipids

Identifiers

PMID35442170
PMCPMC9163648
OpenAlexW4224216730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.