Evidence map›Paper›PMID 35441751›Full record

SynthesisJournal of paediatrics and child health2022

Comparison of ultrasound-guided peripheral intravenous catheter insertion with landmark technique in paediatric patients: A systematic review and meta-analysis.

Tricia M Kleidon, Jessica Schults, Rebecca Paterson, Claire M Rickard, Amanda J Ullman

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of paediatrics and child health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07519304 (Effectiveness of a Needle-free Connector With Anti-reflux Technology in Reducing Complications From Long Peripheral Venous Catheters in Hospitalised Adult Patients), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07519304 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effectiveness of a Needle-free Connector With Anti-reflux Technology in Reducing Complications From Long Peripheral Venous Catheters in Hospitalised Adult Patients: Randomised Clinical Trial

TypeinterventionalSponsorHospital Arnau de VilanovaRan2026 to 2026Enrolled62ConditionsVascular Access Devices, Catheters, Occlusion, ThrombosisArmsNeedle-free connector with neutral fluid displacement and without anti-reflux technology, Needle-free connector with neutral fluid displacement and equipped with anti-reflux technology, Long peripheral venous catheter, Ultrasound scanner
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  3. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tricia M KleidonDepartment of Anaesthesia, Queensland Children's Hospital, Brisbane, Queensland, Australia.ORCID 0000-0001-8369-3970
Jessica SchultsDepartment of Anaesthesia, Queensland Children's Hospital, Brisbane, Queensland, Australia.
Rebecca PatersonDepartment of Anaesthesia, Queensland Children's Hospital, Brisbane, Queensland, Australia.
Claire M RickardDepartment of Anaesthesia, Queensland Children's Hospital, Brisbane, Queensland, Australia.
Amanda J UllmanDepartment of Anaesthesia, Queensland Children's Hospital, Brisbane, Queensland, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPaediatric peripheral intravenous catheter (PIVC) insertion using traditional landmark insertion technique can be difficult.

aimTo systematically review the evidence comparing landmark to ultrasound guidance for PIVC insertion in general paediatric patients. STUDY

designCochrane methodology to systematically search for randomised controlled trials comparing landmark to ultrasound-guided PIVC insertion. DATA SOURCES: Cochrane Central Register of Controlled Trials, US National Library of Medicine, Cumulative Index to Nursing and Allied Health, Embase. DATA EXTRACTION: English-language, paediatric trials published after 2000, reporting first-attempt insertion success, overall PIVC insertion success, and/or time to insert were included. Central venous, non-venous and trials including only difficult intravenous access were excluded. Data were independently extracted and critiqued for quality using GRADE by three authors, and analysed using random effects, with results expressed as risk ratios (RR), mean differences (MD) and 95% confidence intervals (CI). Registration (CRD42020175314).

resultsOf 70 titles identified, 5 studies (995 patients; 949 PIVCs) were included. There was no evidence of an effect of ultrasound guidance, compared to landmark, for first-attempt insertion success (RR 1.27; 95% CI 0.90-1.78; I LIMITATIONS: Small sample sizes, inconsistent outcomes and definitions in primary studies precluded definitive conclusions.

conclusionsLarge clinical trials are needed to explore the effectiveness of ultrasound guidance for PIVC insertion in paediatrics. Specifically, children with difficult intravenous access might benefit most from this technology.

Indexed as

Catheterization, PeripheralPediatricsCathetersChildHumansUltrasonographyUltrasonography, Interventionalcatheterisationperipheralperipheral venous cathetersystematic reviewultrasonographyvascular access device

Identifiers

PMID35441751
PMCPMC9321813

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.