Evidence map›Paper›PMID 35441583›Full record

ArticleBioengineered2022

LINC00173 regulates polycystic ovarian syndrome progression by promoting apoptosis and repressing proliferation in ovarian granulosa cells via the microRNA-124-3p (miR-124-3p)/jagged canonical Notch ligand 1 (JAG1) pathway.

Lan Chen, Caixia Kong

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  7. Expression of Tumor SuppressorInternational journal of molecular sciences · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lan ChenDepartment of Gynecology, Changzhou Hospital of Traditional Chinese Medicine, Changzhou, China.
Caixia KongDepartment of Gynecology, Changzhou Hospital of Traditional Chinese Medicine, Changzhou, China.ORCID 0000-0003-4536-0723
Hangzhou Hospital of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As an endocrine and metabolic disorder, polycystic ovarian syndrome (PCOS) is common in females at childbearing age. Our work was intended to uncover the underlying role of LINC00173 and its potential regulatory mechanism in PCOS based on two cell lines (PCOS granulosa cells and KGN cells) and an

Indexed as

MicroRNAsPolycystic Ovary SyndromeAnimalsApoptosisCell ProliferationFemaleGranulosa CellsHumansJagged-1 ProteinLigandsRatsRats, Sprague-DawleyRNA, UntranslatedJAG1 protein, humanJag1 protein, ratJagged-1 ProteinLigandsMicroRNAsMIRN124 microRNA, humanMIRN124 microRNA, ratRNA, UntranslatedJAG1LINC00173miR-124-3ppolycystic ovarian syndrome

Identifiers

PMID35441583
PMCPMC9161924
OpenAlexW4224226386

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.