Evidence map›Paper›PMID 35441179›Full record

ArticlemedRxiv : the preprint server for health sciences2022

A booster dose of an inactivated SARS-CoV-2 vaccine increases neutralizing antibodies and T cells that recognize Delta and Omicron variants of concern.

Bárbara M Schultz, Felipe Melo-González, Luisa F Duarte, Nicolás Ms Gálvez, Gaspar A Pacheco, Jorge A Soto, Roslye V Berríos-Rojas, Liliana A González, Daniela Moreno-Tapia, Daniela Rivera-Pérez and 27 more

Open access · greenAbstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 10 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

37 authors at 5 institutions in 3 countries.

Bárbara M SchultzORCID 0000-0002-6201-6978
Felipe Melo-GonzálezORCID 0000-0002-3711-2407
Nicolás Ms GálvezORCID 0000-0003-2046-7882
Roslye V Berríos-RojasORCID 0000-0002-6949-9829
Liliana A González
Daniela Moreno-TapiaORCID 0000-0002-2721-8355
Daniela Rivera-PérezORCID 0000-0002-3317-5080
Guillermo Hoppe-ElsholzORCID 0000-0003-2029-9700
Carolina Iturriaga
Marcela Urzua
María S Navarrete
Álvaro Rojas
Jorge Fernández
Judith Mora
Eugenio Ramírez
Aracelly Gaete-Argel
Mónica Acevedo
Fernando Valiente-EcheverríaORCID 0000-0001-9156-2516
Ricardo Soto-Rifo
Daniela Weiskopf
Gang Zeng
Weining Meng
CoronaVac03CL Study Group
José V González-AramundizORCID 0000-0001-7856-9211
Pablo A GonzálezORCID 0000-0001-7709-6870
Alexis M Kalergis
Pontificia Universidad Católica de Chile · CLMillennium Institute on Immunology and Immunotherapy · CLInstituto de Salud Pública de Chile · CLLa Jolla Institute for Immunology · USSinovac Biotech · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: CoronaVac Methods: Volunteers immunized with two doses of CoronaVac Findings: We observed a significant increase in neutralizing antibodies at four weeks after the booster dose. We also observed an increase in CD4 Interpretation: Our results show that a booster dose of CoronaVac

Identifiers

PMID35441179
PMCPMC9016658
OpenAlexW3213115833

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.