Evidence map›Paper›PMID 35441176›Full record

ArticleResearch square2022

Famotidine activates the vagus nerve inflammatory reflex to attenuate cytokine storm.

Huan Yang, Sam J George, Dane Thompson, Harold A Silverman, Tea Tsaava, Aisling Tynan, Valentin A Pavlov, Eric Chang, Ulf Andersson, Michael Brines and 2 more

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Optimization of cellulase production by Albifimbria verrucaria TRQ88 and its application in saccharification of cellulose pulp from wheat straw.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Huan YangFeinstein Institute for Medical Research.ORCID 0000-0001-8796-5523
Sam J GeorgeFeinstein Institute for Medical Research Fertility Research Laboratory: Northwell Health Feinstein Institutes for Medical Research.
Dane ThompsonFeinstein Institute for Medical Research Fertility Research Laboratory: Northwell Health Feinstein Institutes for Medical Research.
Harold A SilvermanFeinstein Institute for Medical Research Fertility Research Laboratory: Northwell Health Feinstein Institutes for Medical Research.
Tea TsaavaFeinstein Institute for Medical Research Fertility Research Laboratory: Northwell Health Feinstein Institutes for Medical Research.
Aisling TynanFeinstein Institute for Medical Research Fertility Research Laboratory: Northwell Health Feinstein Institutes for Medical Research.
Valentin A PavlovFeinstein Institute for Medical Research Fertility Research Laboratory: Northwell Health Feinstein Institutes for Medical Research.
Eric ChangFeinstein Institute for Medical Research Fertility Research Laboratory: Northwell Health Feinstein Institutes for Medical Research.
Ulf AnderssonKarolinska Institutet.
Michael BrinesFeinstein Institute for Medical Research Fertility Research Laboratory: Northwell Health Feinstein Institutes for Medical Research.
Sangeeta S ChavanFeinstein Institute for Medical Research Fertility Research Laboratory: Northwell Health Feinstein Institutes for Medical Research.
Kevin J TraceyFeinstein Institute for Medical Research Fertility Research Laboratory: Northwell Health Feinstein Institutes for Medical Research.
Feinstein Institute for Medical Research · USKarolinska Institutet · SE

Funding

Molecular Basis of Bioelectronic MedicineR35GM118182 · NIGMS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI TRACEY, KEVIN J · 2016 to 2025
$7.3M
The ion channel TRPA1 is required for suppression of inflammation in sepsisR01GM132672 · NIGMS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI CHAVAN, SANGEETA S. · 2019 to 2025
$1.7M
NIGMS NIH HHS R01 GM132672NIGMS NIH HHS R35 GM118182
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID35441176
PMCPMC9016653
OpenAlexW4223527341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.