Evidence map›Paper›PMID 35441132›Full record

ArticleBrain communications2022

Diminished preparatory physiological responses in frontotemporal lobar degeneration syndromes.

Kuan-Hua Chen, Alice Y Hua, Gianina Toller, Sandy J Lwi, Marcela C Otero, Claudia M Haase, Katherine P Rankin, Howard J Rosen, Bruce L Miller, Robert W Levenson

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Diminished preparatory physiological responses in people with dementia: associations with caregiver health and relationship quality.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Interpersonal linkage in positive and negative emotional behaviors, emotional well-being, and physical functioning in dementia caregivers.Clinical psychological science : a journal of the Association for Psychological Science · 2024
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Kuan-Hua ChenDepartment of Psychology, University of California, Berkeley, 2121 Berkeley Way, Berkeley, CA 94720-1650, USA.
Alice Y HuaDepartment of Psychology, University of California, Berkeley, 2121 Berkeley Way, Berkeley, CA 94720-1650, USA.
Gianina TollerMemory & Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA.
Sandy J LwiDepartment of Psychology, University of California, Berkeley, 2121 Berkeley Way, Berkeley, CA 94720-1650, USA.ORCID https://orcid.org/0000-0002-2904-7078
Marcela C OteroDepartment of Psychology, University of California, Berkeley, 2121 Berkeley Way, Berkeley, CA 94720-1650, USA.
Claudia M HaaseDepartment of Human Development and Social Policy, Northwestern University, Evanston, IL 60208, USA.
Katherine P RankinMemory & Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA.
Howard J RosenMemory & Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA.
Bruce L MillerMemory & Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA.
Robert W LevensonDepartment of Psychology, University of California, Berkeley, 2121 Berkeley Way, Berkeley, CA 94720-1650, USA.
University of California, San Francisco · USUniversity of California, Berkeley · USMental Illness Research, Education and Clinical Centers · USNorthwestern University · US

Funding

TDP-43 Loss-of-Function: Biology to BiomarkersP01AG019724 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jennifer Merrilees · 2002 to 2026
$67.2M
PREDOCTORAL TRAINING CONSORTIUM IN AFFECTIVE SCIENCET32MH020006 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI GROSS, JAMES J, JOHNSON, SHERI L · 1998 to 2018
$5.9M
Developing and Evaluating In-Home Supportive Technology for Dementia CaregiversR44AG059458 · NIA · PEOPLE POWER COMPANY · PI WANG, GENE · 2018 to 2020
$4.7M
Commercializing In-Home Supportive Technolgy for Dementia CaregiversSB1AG059458 · NIA · PEOPLE POWER COMPANY · PI WANG, GENE · 2021 to 2022
$3.2M
Burden, Depression, and Health in Dementia Caregivers: The Role of EmotionR01AG041762 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI LEVENSON, ROBERT WAYNE · 2012 to 2016
$2.8M
Multimodal Imaging in Frontotemporal DegenerationK24AG045333 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ROSEN, HOWARD J · 2013 to 2023
$1.9M
Behavioral and physiological linkage in people with frontotemporal dementia and spousal caregiversK99AG059947 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI CHEN, KUAN-HUA · 2019 to 2021
$335k
NIA NIH HHS K24 AG045333NIA NIH HHS K99 AG059947NIA NIH HHS P01 AG019724NIA NIH HHS R01 AG041762NIA NIH HHS R44 AG059458NIA NIH HHS SB1 AG059458NIMH NIH HHS T32 MH020006
6 · The paper itself

Abstract

Researchers typically study physiological responses either after stimulus onset or when the emotional valence of an upcoming stimulus is revealed. Yet, participants may also respond when they are told that an emotional stimulus is about to be presented even without knowing its valence. Increased physiological responding during this time may reflect a 'preparation for action'. The generation of such physiological responses may be supported by frontotemporal regions of the brain that are vulnerable to damage in frontotemporal lobar degeneration. We examined preparatory physiological responses and their structural and functional neural correlate in five frontotemporal lobar degeneration clinical subtypes (behavioural variant frontotemporal dementia,

Indexed as

lesionpsychophysiologyresting-state fMRIvoxel-based morphometry

Identifiers

PMID35441132
PMCPMC9014451
OpenAlexW4224083864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.