Evidence map›Paper›PMID 35441129›Full record

ArticleCardiovascular endocrinology & metabolism2022

Reducing fatigue-related symptoms in Long COVID-19: a preliminary report of a lymphatic drainage intervention.

Adrian Heald, Raymond Perrin, Andreas Walther, Mike Stedman, Mark Hann, Annice Mukherjee, Lisa Riste

Open access · diamondAbstract read
In one paragraph

Article in Cardiovascular endocrinology & metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Adrian HealdThe School of Health Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester.
Raymond PerrinThe School of Health Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester.
Andreas WaltherThe University of Zurich, Zurich, Switzerland.
Mike StedmanRes Consortium, Andover.
Mark HannManchester Academic Health Sciences Centre, University of Manchester School of Health Sciences and.
Annice MukherjeeThe School of Health Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester.
Lisa RisteThe School of Health Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester.
University of Manchester · GBConcord Consortium · USManchester Academic Health Science Centre · GBNIHR Manchester Biomedical Research Centre · GBUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the early days of the first global wave of the COVID-19 pandemic, the potential for a postviral syndrome to manifest following COVID-19 infection was first recognized. Here, we present an analysis of a case series of the first 20 patients' data collected in clinical practice to evaluate the potential of a possible alternative treatment for Long COVID. Methods: Face-to-face treatment sessions with Perrin technique practitioners occurred weekly involving effleurage/other manual articulatory techniques. The individuals being treated also undertook daily self-massage along with gentle mobility exercises. Patients recorded symptom severity using the self-report 54-item profile of fatigue-related states (PFRS) before and after treatment. Results: The mean age of male patients was 41.8 years (range, 29-53 years), and for female patients, 39.3 years (range, 28-50 years). None of the participants had a prior diagnosis of chronic fatigue syndrome, and all were new attendees to the clinics at the time of initial assessment. The average number of treatment sessions was 9.7 in men and 9.4 in women. The reduction in PFRS scores was 45% in men and 52% in women. The highest subscale scores on average were for fatigue, with the lowest for somatic symptoms. All subscale scores showed, on average, a similar reduction of approximately 50% postintervention, with the reduction in score relating to a decrease in the severity of symptoms. Conclusion: Our findings suggest that a specific manual lymphatic drainage intervention may help to reduce fatigue symptoms related to Long COVID. Perhaps preventing acute symptoms through early intervention.

Indexed as

fatigueLong COVIDlymphatic drainagetreatment

Identifiers

PMID35441129
PMCPMC9010124
OpenAlexW4223948898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.