Evidence map›Paper›PMID 35441015›Full record

ArticleClinical case reports2022

Guillain-Barré syndrome after mRNA-1273 (Moderna) COVID-19 vaccination: A case report.

Zauraiz Anjum, Charoo Iyer, Sidra Naz, Vikash Jaiswal, Gaurav Nepal, Maryrose Laguio-Vila, Sanjay Anandaram, Sahil Thapaliya

Abstract readCase Reports
In one paragraph

Article in Clinical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zauraiz AnjumRochester General Hospital Rochester New York USA.
Charoo IyerRochester General Hospital Rochester New York USA.
Sidra NazHarvard Medical School Boston Massachusetts USA.ORCID https://orcid.org/0000-0001-6390-9658
Vikash JaiswalAMA school of medicine Makati Philippines.ORCID https://orcid.org/0000-0002-2021-1660
Gaurav NepalTribhuvan University Institute of Medicine Kathmandu Nepal.ORCID https://orcid.org/0000-0001-5054-2711
Maryrose Laguio-VilaRochester General Hospital Rochester New York USA.
Sanjay AnandaramRochester General Hospital Rochester New York USA.
Sahil ThapaliyaTribhuvan University Institute of Medicine Kathmandu Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Guillain-Barre syndrome (GBS) is an acquired inflammatory polyradiculoneuropathy that often follows infection with a virus or bacteria and in rare occasions, vaccination may precede GBS. We present a case of 80-year-old male patient who presented with chief complaints of progressive, ascending bilateral lower extremity paresthesia and weakness following first dose of Moderna vaccine. His symptoms got exacerbated after 2nd dose. Clinical examination and investigation findings including lumbar puncture, nerve conduction study, and electromyography were consistent with the diagnosis of GBS. The patient received treatment with intravenous immunoglobulin and there was significant improvement toward the end of 5th day. Though rare, this case report suggest that physician should remain vigilant for GBS following COVID-19 vaccination.

Indexed as

COVID‐19GBSModernamRNAvaccine

Identifiers

PMID35441015
PMCPMC9010569

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.