Evidence map›Paper›PMID 35440936›Full record

ArticleFood & nutrition research2022

Administration of Jerusalem artichoke reduces the postprandial plasma glucose and glucose-dependent insulinotropic polypeptide (GIP) concentrations in humans.

Hirokazu Takahashi, Akane Nakajima, Yuichi Matsumoto, Hitoe Mori, Kanako Inoue, Hiroko Yamanouchi, Kenichi Tanaka, Yuki Tomiga, Maki Miyahara, Tomomi Yada and 4 more

Open access · goldAbstract read
In one paragraph

Article in Food & nutrition research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Hirokazu TakahashiDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga, Japan.
Akane NakajimaDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga, Japan.
Yuichi MatsumotoCenter for Education and Research in Agricultural Innovation, Faculty of Agriculture, Saga University, Karatsu, Saga, Japan.
Hitoe MoriDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga, Japan.
Kanako InoueDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga, Japan.
Hiroko YamanouchiDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga, Japan.
Kenichi TanakaDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga, Japan.
Yuki TomigaDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga, Japan.
Maki MiyaharaDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga, Japan.
Tomomi YadaDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga, Japan.
Yumiko IbaCenter of Nutritional Education, Saga University Hospital, Faculty of Medicine, Saga University, Saga, Japan.
Yayoi MatsudaDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga, Japan.
Keiichi WatanabeCenter for Education and Research in Agricultural Innovation, Faculty of Agriculture, Saga University, Karatsu, Saga, Japan.
Keizo AnzaiDivision of Metabolism and Endocrinology, Faculty of Medicine, Saga University, Saga, Japan.
Saga University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The consumption of Jerusalem artichoke has multiple beneficial effects against diabetes and obesity. Objective: The aim of this study was to determine the effect of a single administration of Jerusalem artichoke tubers on postprandial glycemia and the concentrations of incretin hormones in humans. Method: Grated Jerusalem artichoke was administered prior to a meal (Trial 1; white rice for prediabetic participants, Results: Jerusalem artichoke significantly reduced the glucose and GIP concentrations after the consumption of either meal in Trial 1 and Trial 3, whereas there were no differences in the insulin, glucagon, and active GLP-1 concentrations. Also, there was no significant difference in the triglyceride concentration after the ingestion of the fat-rich meal in Trial 3. The glucose and GIP-lowering effects were dose-dependent, and the consumption of at least 100 g of Jerusalem artichoke was required to have these effects in Trial 2. Conclusion: This study demonstrates that a single administration of Jerusalem artichoke tubers reduces postprandial glucose and active GIP concentrations in prediabetic and healthy individuals.

Indexed as

diabetes mellitusglucagon-like peptide-1impaired glucose toleranceincretinKikuimoTopinambou

Identifiers

PMID35440936
PMCPMC8985572
OpenAlexW4226196755

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.