ReviewNature medicine2022
Priorities for cancer research in low- and middle-income countries: a global perspective.
Review in Nature medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 203 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
203 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Effectiveness of Continuity of Care Interventions Linking Hospital Care to Primary Healthcare for Patients With Cancer: A Systematic Review and Meta-Analysis.Cancer medicine · 2026Pooled it
- Prescription and use of psychoactive medications among cancer patients and associated factors in lower and upper middle-income countries: systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Pooled it
- Physical late effects of treatment among survivors of childhood cancer in low- and middle-income countries: a systematic review.Journal of cancer survivorship : research and practice · 2025Pooled it
- The prognostic significance of lncRNA FGD5-AS1 in various malignancies: a meta-analysis.Frontiers in oncology · 2024Pooled it
- Prognostic significance of long noncoding RNA TTN-AS1 in various malignancies.Cancer reports (Hoboken, N.J.) · 2023Pooled it
- Cost Drivers and Financial Burden for Cancer-Affected Families in China: A Systematic Review.Current oncology (Toronto, Ont.) · 2023Pooled it
- Effectiveness of Skill-Building Interventions for Informal Caregivers of Adults with Cancer: a Systematic Review.Journal of cancer education : the official journal of the American Association for Cancer Education · 2023Pooled it
- Mobile-Based Application Interventions to Enhance Cancer Control and Care in Low- and Middle-Income Countries: A Systematic Review.International journal of public health · 2023Pooled it
- The patient, diagnostic, and treatment intervals in adult patients with cancer from high- and lower-income countries: A systematic review and meta-analysis.PLoS medicine · 2022Pooled it
- Disease Burden of Early-Onset Pancreatic Cancer in Adults Aged 20-54 Years in Low- and Middle-Income Countries: A GBD 2023 Analysis.Digestive diseases and sciences · 2026Article
- Modifiable lifestyle factors and cancer risk in Latin America: A systematic review with meta-analysis.iScience · 2026Article
- Independent cancer research in low- and middle-income countries: why it matters and how to build it.The oncologist · 2026Review
- Limited inclusion in clinical trials and access to poly (ADP-ribose) polymerase inhibitors in racial and ethnic minority patients with cancer: a narrative review.The oncologist · 2026Review
- Mapping stakeholders for developing cancer research in Small Island Developing States: a descriptive study from the Eastern Caribbean.BMJ open · 2026Article
- Multidisciplinary Team Care for Early-Stage Lung Cancer in Low- and Middle-Income Countries and Emerging Economies: Current Position and Call for Action.Thoracic cancer · 2026Review
- Closing the Translational Gap: Closed-Loop AI Discovery Frameworks for Experimental Validation and Clinical Implementation in Cancer Therapeutics.Cancer medicine · 2026Review
- Political determinants of melanoma: Global inequities in skin cancer care.JAAD international · 2026Article
- Early-onset cancer in Latin America: incidence trends, evidence gaps and clinical implications.EClinicalMedicine · 2026Review
- Global patterns of melanoma, burden attributable to ultraviolet radiation exposure, and projections to 2050 across 185 countries: A population-based study with global modeling.JAAD international · 2026Article
143 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors.
Funding
Abstract
Cancer research currently is heavily skewed toward high-income countries (HICs), with little research conducted in, and relevant to, the problems of low- and middle-income countries (LMICs). This regional discordance in cancer knowledge generation and application needs to be rebalanced. Several gaps in the research enterprise of LMICs need to be addressed to promote regionally relevant research, and radical rethinking is needed to address the burning issues in cancer care in these regions. We identified five top priorities in cancer research in LMICs based on current and projected needs: reducing the burden of patients with advanced disease; improving access and affordability, and outcomes of cancer treatment; value-based care and health economics; quality improvement and implementation research; and leveraging technology to improve cancer control. LMICs have an excellent opportunity to address important questions in cancer research that could impact cancer control globally. Success will require collaboration and commitment from governments, policy makers, funding agencies, health care organizations and leaders, researchers and the public.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.