Evidence map›Paper›PMID 35440709›Full record

ArticleCommunications biology2022

Cellular and molecular signatures of in vivo imaging measures of GABAergic neurotransmission in the human brain.

Paulina Barbara Lukow, Daniel Martins, Mattia Veronese, Anthony Christopher Vernon, Philip McGuire, Federico Edoardo Turkheimer, Gemma Modinos

Abstract read
In one paragraph

Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. GABAMolecular psychiatry · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. GABANeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paulina Barbara LukowDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16 De Crespigny Park, SE5 8AF, London, UK. paulina.lukow@kcl.ac.uk.ORCID 0000-0002-6796-9102
Daniel MartinsDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16 De Crespigny Park, SE5 8AF, London, UK.ORCID 0000-0002-0239-8206
Mattia VeroneseDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16 De Crespigny Park, SE5 8AF, London, UK.ORCID 0000-0003-3562-0683
Anthony Christopher VernonDepartment of Basic & Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, 5 Cutcombe Road, Brixton, London, SE5 9RT, UK.ORCID 0000-0001-7305-1069
Philip McGuireDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16 De Crespigny Park, SE5 8AF, London, UK.ORCID 0000-0003-4381-0532
Federico Edoardo TurkheimerDepartment of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16 De Crespigny Park, SE5 8AF, London, UK.ORCID 0000-0002-3766-3815
Gemma ModinosDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16 De Crespigny Park, SE5 8AF, London, UK.ORCID 0000-0002-7870-066X

Funding

Department of HealthMedical Research Council MR/K022733/1Medical Research Council MR/N026063/1Medical Research Council MR/W006251/1Wellcome Trust 202397/Z/16/Z
6 · The paper itself

Abstract

Diverse GABAergic interneuron networks orchestrate information processing in the brain. Understanding the principles underlying the organisation of this system in the human brain, and whether these principles are reflected by available non-invasive in vivo neuroimaging methods, is crucial for the study of GABAergic neurotransmission. Here, we use human gene expression data and state-of-the-art imaging transcriptomics to uncover co-expression patterns between genes encoding GABA

Indexed as

FlumazenilReceptors, GABA-ABrainHumansNeuroimagingSynaptic TransmissionFlumazenilReceptors, GABA-A

Identifiers

PMID35440709
PMCPMC9018713

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.