Evidence map›Paper›PMID 35440592›Full record

ArticleNature communications2022

A fully automatic AI system for tooth and alveolar bone segmentation from cone-beam CT images.

Zhiming Cui, Yu Fang, Lanzhuju Mei, Bojun Zhang, Bo Yu, Jiameng Liu, Caiwen Jiang, Yuhang Sun, Lei Ma, Jiawei Huang and 6 more

Abstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. [Research on automated orthodontic tooth arrangement by integrating multi-source structural information and dental arch prediction].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
    Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article

49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Zhiming Cui *School of Biomedical Engineering, ShanghaiTech University, Shanghai, 201210, China.ORCID 0000-0002-3798-4504
Yu Fang *School of Biomedical Engineering, ShanghaiTech University, Shanghai, 201210, China.ORCID 0000-0001-5121-3581
Lanzhuju Mei *School of Biomedical Engineering, ShanghaiTech University, Shanghai, 201210, China.ORCID 0000-0001-7753-6207
Bojun Zhang *Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200011, China.
Bo YuSchool of Public Health, Hangzhou Medical College, Hangzhou, 310013, China.
Jiameng LiuSchool of Biomedical Engineering, ShanghaiTech University, Shanghai, 201210, China.
Caiwen JiangSchool of Biomedical Engineering, ShanghaiTech University, Shanghai, 201210, China.
Yuhang SunSchool of Biomedical Engineering, ShanghaiTech University, Shanghai, 201210, China.
Lei MaSchool of Biomedical Engineering, ShanghaiTech University, Shanghai, 201210, China.
Jiawei HuangSchool of Biomedical Engineering, ShanghaiTech University, Shanghai, 201210, China.
Yang LiuDepartment of Orthodontics, Stomatological Hospital of Chongqing Medical University, Chongqing, 401147, China.
Yue ZhaoSchool of Communication and Information Engineering, Chongqing University of Posts and Telecommunications, Chongqing, 400065, China. zhaoyue@cqupt.edu.cn.
Chunfeng LianSchool of Mathematics and Statistics, Xi'an Jiaotong University, Xi'an, 710049, China. chunfeng.lian@xjtu.edu.cn.
Zhongxiang DingDepartment of Radiology, Hangzhou First People's Hospital, Zhejiang University, Hangzhou, 310006, China. hangzhoudzx73@126.com.
Min ZhuShanghai Ninth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200011, China. ZHUM1612@sh9hospital.org.cn.
Dinggang ShenSchool of Biomedical Engineering, ShanghaiTech University, Shanghai, 201210, China. dgshen@shanghaitech.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate delineation of individual teeth and alveolar bones from dental cone-beam CT (CBCT) images is an essential step in digital dentistry for precision dental healthcare. In this paper, we present an AI system for efficient, precise, and fully automatic segmentation of real-patient CBCT images. Our AI system is evaluated on the largest dataset so far, i.e., using a dataset of 4,215 patients (with 4,938 CBCT scans) from 15 different centers. This fully automatic AI system achieves a segmentation accuracy comparable to experienced radiologists (e.g., 0.5% improvement in terms of average Dice similarity coefficient), while significant improvement in efficiency (i.e., 500 times faster). In addition, it consistently obtains accurate results on the challenging cases with variable dental abnormalities, with the average Dice scores of 91.5% and 93.0% for tooth and alveolar bone segmentation. These results demonstrate its potential as a powerful system to boost clinical workflows of digital dentistry.

Indexed as

Image Processing, Computer-AssistedToothArtificial IntelligenceCone-Beam Computed TomographyHumansWorkflow

Identifiers

PMID35440592
PMCPMC9018763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.