ArticleNature communications2022
Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca
Open access · goldAbstract read
In one paragraph
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 36 citations in OpenAlex.
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- The Potential Role of Calcium Channels in Pulmonary Hypertension.BioMed research international · 2026Review
- CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity.Science immunology · 2025Article
- Apoptotic Vesicles Derived from Mesenchymal Stem Cells Ameliorate Hypersensitivity Responses via Inducing CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Mapping the interaction surface between CaNature communications · 2025Article
- STIM1-mediated NFAT signaling synergizes with STAT1 to control T-bet expression and TNature immunology · 2025Article
- Calcium Channel Blocker Lacidipine Promotes Antitumor Immunity by Reprogramming Tryptophan Metabolism.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Genetic evidence against involvement of TRPC proteins in SOCE, ROCE, and CRAC channel function.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- T-Type Voltage-Gated Calcium Channels: Potential Regulators of Smooth Muscle Contractility.International journal of molecular sciences · 2024Review
- Sex and age affect depot expression of Ca2+ channels in rat white fat adipocytes.Journal of molecular endocrinology · 2024Article
- SOCE as a regulator of neuronal activity.The Journal of physiology · 2024Review
- Illuminating the druggable genome: Pathways to progress.Drug discovery today · 2024Review
- Establishing an ANO1-Based Cell Model for High-Throughput Screening Targeting TRPV4 Regulators.Molecules (Basel, Switzerland) · 2024Article
- Benidipine impairs innate immunity converting sublethal to lethal infections in a murine model of spotted fever rickettsiosis.PLoS neglected tropical diseases · 2024Article
- Bioelectricity in dental medicine: a narrative review.Biomedical engineering online · 2024Review
- Structure of the voltage-gated potassium channel KChannels (Austin, Tex.) · 2023Review
- Repurposing Verapamil to Enhance Killing of T-ALL Cells by the mTOR Inhibitor Everolimus.Antioxidants (Basel, Switzerland) · 2023Article
- Ion Channels and Transporters in Immunity-Where do We Stand?Function (Oxford, England) · 2023Article
Corrections and comments
- Commented on byVoltage-gated Ca2022
Authors and funding
15 authors at 8 institutions in 2 countries.
Serap Erdogmus *Department of Pathology, NYU Grossman School of Medicine, New York, NY, USA.
Axel R Concepcion *Department of Pathology, NYU Grossman School of Medicine, New York, NY, USA.
Megumi YamashitaDepartment of Pharmacology, Northwestern University, Chicago, IL, USA.
Ikjot SidhuDepartment of Pathology, NYU Grossman School of Medicine, New York, NY, USA.
Anthony Y TaoDepartment of Pathology, NYU Grossman School of Medicine, New York, NY, USA.
Wenyi LiDepartment of Pathology, NYU Grossman School of Medicine, New York, NY, USA.ORCID 0000-0002-5436-1317
Pedro P RochaUnit on Genome Structure and Regulation, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-4691-7773
Bonnie HuangNational Institute of Allergy and Infectious Disease, Bethesda, MD, USA.ORCID 0000-0001-5931-6075
Ralph GarippaDepartment of Cancer Biology & Genetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Boram LeeDepartment of Pharmacology, University of California, Davis, CA, USA.
Amy LeeDepartment of Neuroscience, University of Texas-Austin, Austin, TX, USA.
Johannes W HellDepartment of Pharmacology, University of California, Davis, CA, USA.ORCID 0000-0001-7960-7531
Richard S LewisDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA.
Murali PrakriyaDepartment of Pharmacology, Northwestern University, Chicago, IL, USA. m-prakriya@northwestern.edu.
Stefan FeskeDepartment of Pathology, NYU Grossman School of Medicine, New York, NY, USA. feskes01@nyumc.org.ORCID 0000-0001-5431-8178
New York University · USNorthwestern University · USUniversity of California, Davis · USMemorial Sloan Kettering Cancer Center · USNational Human Genome Research Institute · USNational Institutes of Health · USStanford University · USThe University of Texas at Austin · US
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4MGenome 3D organization as a determinant of cell-fate decisionsZIAHD008975 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI ROCHA, PEDRO · 2018 to 2025
$10.4MIon Channels and Signaling Mechanisms in T LymphocytesR37GM045374 · NIGMS · STANFORD UNIVERSITY · PI LEWIS, RICHARD S · 2012 to 2021
$6.2MCRAC Channel Deficiency in Immunity to InfectionR01AI097302 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2012 to 2022
$5.6MStore-Operated Channels in the Nervous SystemR01NS057499 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PRAKRIYA, MURALI · 2007 to 2022
$5.4MION CHANNELS AND SIGNALING MECHANISMS IN T LYMPHOCYTESR01GM045374 · NIGMS · STANFORD UNIVERSITY · PI LEWIS, RICHARD S · 1991 to 2011
$5.0MTraining Program in Immunology and Inflammation.T32AI100853 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Susan Ruth Schwab · 2012 to 2026
$4.5MCalcium channels in retinal photoreceptorsR01EY026817 · NEI · UNIVERSITY OF TEXAS AT AUSTIN · PI LEE, AMY · 2017 to 2025
$4.4MRole of a-actinin in Cav1.2 FunctionR01AG055357 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JOHANNES W HELL · 2016 to 2026
$4.0MDysregulation of Cav1.2 by beta amyloid peptideRF1AG055357 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2022 to 2024
$1.7MIdentifying Novel Ion Channels Regulating T cell FunctionR21AI125997 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2016 to 2017
$466kStore-operated channels in the nervous systemR56NS057499 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PRAKRIYA, MURALI · 2012 to 2012
$344kNCATS NIH HHS R03 TR002873NCI NIH HHS P30 CA008748NEI NIH HHS R01 EY026817NIAID NIH HHS R01 AI097302NIAID NIH HHS R21 AI125997NIAID NIH HHS T32 AI100853NIA NIH HHS R01 AG055357NIA NIH HHS RF1 AG055357NIGMS NIH HHS R01 GM045374NIGMS NIH HHS R37 GM045374NINDS NIH HHS R01 NS057499NINDS NIH HHS R56 NS057499
Abstract
TCR stimulation triggers Ca
Indexed as
ApoptosisT-LymphocytesAnimalsCalcium Channels, L-TypeCell ProliferationMiceReceptors, Antigen, T-CellCacnb1 protein, mouseCalcium Channels, L-TypeReceptors, Antigen, T-Cell
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.