ArticleBMC pregnancy and childbirth2022
A longitudinal cohort study of gestational diabetes mellitus and perinatal depression.
Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Gestational diabetes and risk of perinatal depression in low- and middle-income countries: a meta-analysis.Frontiers in psychiatry · 2024Pooled it
- GDM-Related Neurodevelopmental and Neuropsychiatric Disorders in the Mothers and Their Progeny, and the Underlying Mechanisms.Journal of personalized medicine · 2026Review
- The relationship between family function and behavioral decision-making in patients with gestational diabetes mellitus: a multiple mediation model and cross-lagged analysis of pregnancy-related anxiety and hope.Frontiers in medicine · 2026Article
- Is a History of Gestational Diabetes Associated With Long-Term Mental Health?-Findings From the GEMS 5-Year Follow Up Study.Brain and behavior · 2025Article
- Association Between Gestational Diabetes Mellitus and Maternal Depression: A Narrative Review.Cureus · 2025Review
- Negative impact of maternal depressive symptoms on infancy neurodevelopment: a moderated mediation effect of maternal inflammation.European child & adolescent psychiatry · 2025Article
- Gestational diabetes mellitus and peripartum depression: a longitudinal study of a bidirectional relationship.BMC pregnancy and childbirth · 2024Article
- Factors associated with antenatal depression among women attending antenatal care at Mubende Regional Referral Hospital: a cross-sectional study.BMC women's health · 2024Article
- Influencing factors for postpartum depression in women with gestational diabetes mellitus.Frontiers in endocrinology · 2024Article
- Joint effects of recent stressful life events and adverse childhood experiences on perinatal comorbid anxiety and depression.BMC pregnancy and childbirth · 2023Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe association between gestational diabetes mellitus (GDM) and perinatal depression (PND) remains controversial. Our study aimed to comprehensively assess this association in a longitudinal cohort study with repeated measurements of depression.
methodsOur cohort study was nested in a pilot study of an implementation study aiming to screen and manage perinatal depression within the primary health system in China. Women were recruited in the first trimester from May-September 2019 and followed four times up to 1 year postpartum. Data on sociodemographic characteristics and depression were collected using self-developed questionnaires incorporating the Edinburgh Postnatal Depression Scale (EPDS). Oral glucose tolerance test at 24 ~ 28 weeks and fasting plasma glucose (FPG) data were extracted from medical records. Depression throughout the whole period was divided into different trajectories. Associations of GDM with PND at different time periods and PND of different trajectories were determined by logistic regression. The path of association between blood glucose and depression over time was estimated with an autoregressive cross-lagged model.
resultsIn total, 1043 women were included in this analysis and 313 (30.0%) were diagnosed with GDM. The prevalence of depression in the first, second, and third trimesters and postpartum period were 17.2, 6.9, 6.8 and 9.0%, respectively. GDM was neither significantly associated with PND at any time point nor with any specific trajectory of depression. Except for autoregressive paths, no cross-lagged path of FPG and scores of EPDS was significant.
conclusionsOur study indicates no association between GDM/blood glucose and PND.
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