ArticleBMC nephrology2022
Duration of delayed graft function and its impact on graft outcomes in deceased donor kidney transplantation.
Article in BMC nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- No association between delayed graft function and BK polyomavirus infection reactivation after kidney transplantation: a systematic review and meta-analysis.Frontiers in nephrology · 2026Pooled it
- Clinical outcomes of deceased donor kidney transplantation: Eight years of experience from a tertiary care center in India.World journal of nephrology · 2026Article
- The Benefit of Sequential Normothermic Regional Perfusion and Hypothermic Machine Perfusion in Kidney Transplantation From Donation After Circulatory Death Donors.Clinical transplantation · 2026Article
- Machine Learning-Assisted FTIR Spectroscopy Analysis of Kidney Preservation Fluids for Delayed Graft Function Risk Stratification.Journal of clinical medicine · 2026Article
- Comparative Impact of Early Graft Function on Kidney Transplantation Outcomes According to Donor Types.Kidney360 · 2026Article
- The road to 100: single center experience with the first 100 consecutive robotic kidney transplants.Journal of robotic surgery · 2026Article
- Changes by Era in Risk Factors and Outcomes Among Deceased Donor Kidney Transplant Recipients With Delayed Graft Function.Clinical transplantation · 2026Article
- Association Between Perioperative Dexmedetomidine Exposure and Post-Transplant Renal Outcomes: A Retrospective Analysis.Drug design, development and therapy · 2026Article
- Accuracy of oxidative stress markers for predicting delayed graft function lasting longer than a week in deceased-donor kidney transplantation.Einstein (Sao Paulo, Brazil) · 2026Article
- Rationale for Targeting Complement to Mitigate Renal Transplant Ischemia-Reperfusion Injury.Journal of the American Society of Nephrology : JASN · 2026Review
- Biomarker Prediction of Delayed Graft Function and Prognosis Post-Kidney Transplantation.Kidney international reports · 2026Article
- Impact of delayed graft function on overall and graft survival in recipients of deceased donor kidney transplants.BMC nephrology · 2025Article
- Association between delayed graft function and cytomegalovirus infection after renal transplant.Translational andrology and urology · 2025Article
- Posttransplant diabetes mellitus (PTDM) frequency, risk factors, and outcomes: a single-center experience.BMC nephrology · 2025Observational
- Reduced Surgical Complications After Deceased-Donor Kidney Transplantation Using Inverted Allograft and Ultrashort Ureteroureterostomy: A Single-Center Experience.Clinical transplantation · 2025Article
- The Enhanced Recovery After Surgery Pathway Is Safe, Feasible and Cost-Effective in Delayed Graft Function After Kidney Transplant.Journal of clinical medicine · 2025Article
- Article
- Association of glucagon-like peptide-1 receptor agonists with cardiovascular and kidney outcomes in type 2 diabetic kidney transplant recipients.Cardiovascular diabetology · 2025Article
- Donor Characteristics Associated With Graft Loss and Delayed Graft Function in Very-Aged Kidney Donors: An Observational Multicentric Study.Transplant international : official journal of the European Society for Organ Transplantation · 2025Observational
- Delayed graft function after renal transplantation.Open medicine (Warsaw, Poland) · 2025Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is controversy regarding the impact of delayed graft function (DGF) on kidney transplant outcomes. We hypothesize that the duration of DGF, rather than DGF itself, is associated with long-term kidney graft function.
methodsWe analyzed all deceased donor kidney transplants (DDKT) done at our center between 2008 to 2020. We determined factors associated with DGF duration. DGF duration was assessed at three 14-day intervals: < 14 DGF days, 14-27 DGF days, > 28 DGF days. We studied the impact of DGF duration on survival and graft function and resource utilization, including hospital length of stay and readmissions.
results1714 DDKT recipients were included, 59.4% (n = 1018) had DGF. The median DGF duration was 10 days IQR (6,15). The majority of recipients (95%) had resolution of DGF within 28 days. Donor factors associated with DGF days were longer cold ischemia time, donor on inotropes, older age, donation after circulatory death, higher terminal creatinine, and hypertension. Recipient factors associated with increased DGF duration included male sex, length on dialysis before transplant, and higher body mass index. There were no differences in acute rejection events or interstitial fibrosis progression by 4 months when comparing DGF days. The median length of stay was 3 days. However, readmissions increased with increasing DGF duration. Death-censored graft survival was not associated with the length of DGF except when DGF lasted > 28 days.
conclusionsInferior graft survival was observed only in recipients of DDKT with DGF lasting beyond 28 days. DGF lasting < 28 days had no impact on graft survival. Duration of DGF, rather than DGF itself, is associated with graft survival.
trial registrationRetrospective study approved by Mayo Clinic IRB number ID: 20-011561.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.