ArticleBMC health services research2022
An assessment of implementation and effectiveness of mass drug administration for prevention and control of schistosomiasis and soil-transmitted helminths in selected southern Malawi districts.
Article in BMC health services research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Vector borne disease control interventions in agricultural and irrigation areas in sub-Saharan Africa: A systematic review.PloS one · 2025Pooled it
- Mass drug administration campaigns: comparing two approaches for schistosomiasis and soil-transmitted helminths prevention and control in selected Southern Malawi districts.BMC health services research · 2024Trial
- Correlates of prior HIV testing and schistosomiasis treatment: Baseline survey findings from the "creating demand for fishermen's schistosomiasis HIV services" (FISH) cluster-randomized trial in Mangochi, Malawi.PLoS neglected tropical diseases · 2023Trial
- The impact of the termination of Lymphatic Filariasis mass drug administration on Soil-transmitted Helminth prevalence in school children in Malawi.PLoS neglected tropical diseases · 2026Article
- Schistosomiasis amongst adolescent boys in non-lakeshore southern Malawi: Investigating local risk-factors within a nested community-based cross-sectional survey.PLoS neglected tropical diseases · 2025Article
- Reversible paralysis in pregnancy, thinking beyond malaria: a case report.BMC infectious diseases · 2025Article
- Current state and future directions of interventions for neglected tropical diseases.Nature human behaviour · 2025Review
- High Levels of Community Support for Mansonellosis Interventions in an Endemic Area of the Brazilian Amazon.Tropical medicine and infectious disease · 2025Article
- Tetrylpyamethrazine alleviates hepatic fibrosis induced by experimental mansonic schistosomiasis.Inflammopharmacology · 2025Article
- A first report of Biomphalaria pfeifferi in the Lower Shire Valley, Southern Malawi, a major intermediate snail host species for intestinal schistosomiasis.Scientific reports · 2025Article
- Revealing caprine schistosomiasis and its One Health importance in Malawi: A molecular epidemiological investigation augmented with a praziquantel treatment and GPS animal tracking pilot sub-study.One health (Amsterdam, Netherlands) · 2024Article
- Knowledge, Perceptions, Challenges and opportunities in achieving sustainable coverage of mass drug administration towards the control and elimination of Schistosomiasis and Soil Transmitted Helminths in hard-to-reach communities of Ghana.PLoS neglected tropical diseases · 2024Article
- Article
- Prevalence and intensity of soil-transmitted helminth infections among school-aged children in five districts in Uganda.PLoS neglected tropical diseases · 2024Article
- Article
- "Our desire is to make this village intestinal worm free": Identifying determinants of high coverage of community-wide mass drug administration for soil transmitted helminths in Benin, India, and Malawi.PLoS neglected tropical diseases · 2024Article
- Exploring the Role of Community Involvement in Reducing the Burden of Schistosomiasis and Other Neglected Tropical Diseases in Malawi: Where are We in the Fight Against Neglected Tropical Diseases?Research and reports in tropical medicine · 2024Article
- Article
- A baseline epidemiological survey for malaria and schistosomiasis reveals an alarming burden in primary schools despite ongoing control in Chikwawa District, southern Malawi.Current research in parasitology & vector-borne diseases · 2024Article
- Epidemiology of intestinal helminthiasis with an emphasis on taeniasis in Chipata district of the Eastern province of Zambia.PLoS neglected tropical diseases · 2023Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundMass drug administration (MDA) is one of the key interventions recommended by WHO for prevention and control of neglected tropical diseases (NTD). In Malawi, MDA is widely carried out annually since 2009 for prevention and control of schistosomiasis and soil-transmitted helminths (STH). No study has been carried out to assess effectiveness of the MDA approach and to document perceptions of health providers and beneficiaries regarding use of MDA. This study was done to understand how well MDA is being implemented and to identify opportunities for improvement in MDA delivery in Malawi.
methodsDesigned as a cross-sectional and multi-methods research, the study was carried out in three southern Malawi districts of Chiradzulu, Mangochi and Zomba. In each district, four health centres and 16 villages were randomly selected to participate. A mixed-methods approach to data collection focusing on quantitative data for coverage and knowledge, attitudes and practices assessments; and qualitative data for assessing perceptions of health providers and beneficiaries regarding MDA was used. Quantitative data were processed and analyzed using IBM SPSS software version 26 while qualitative data were analysed using NVivo 12 for Windows.
resultsKnowledge levels about schistosomiasis and STH in the districts varied according to disease aspects asked about. Majority are more knowledgeable about what schistosomiasis is (78%) and whether STH are treatable with drugs (97%); with least knowledgeable about the organism that transmits schistosomiasis (18%), types of schistosomiasis (11%) and what causes STH (20%). In 2018 and 2019 the districts registered high coverage rates for praziquantel and albendazole using community-based MDA (73-100%) and using school-based MDA (75-91%). Both the health authorities and community members perceived the MDA approach as good because it brings treatment closer to people.
conclusionWith the high MDA coverage obtained in communities and schools, the effectiveness of MDA in the target districts is satisfactory. There are, however, several challenges including disproportionate knowledge levels, which are hampering progress towards attainment of the 2030 global NTD goals. There is a need for promotion of community participation and partnerships as well as implementation of other recommended interventions for sustainable prevention and control of schistosomiasis and STH.
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