ArticleBMC pregnancy and childbirth2022
Evaluation of neural tube defects from 2014 to 2019 in Turkey.
Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Prevalence and Case Fatality of Congenital Heart Disease in Pakistani Infants: A 11-Year Retrospective Time-Series Analysis.Health science reports · 2026Article
- Awareness and Use of Folic Acid Among Pregnant Women in Western Ukraine: A Pilot Study.International journal of environmental research and public health · 2026Article
- Unusual Comorbid Condition in a Child with Severe Factor XI Deficiency: Spina BifidaTurkish journal of haematology : official journal of Turkish Society of Haematology · 2025Article
- Differential Effects of Green Space Typologies on Congenital Anomalies: Data from the Korean National Health Insurance Service (2008-2013).Healthcare (Basel, Switzerland) · 2025Article
- Clinical and epidemiological profile of neonatal neural tube defects in Turkey: a nationwide retrospective cohort analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Mortality in Cleft Lip and Palate Patients: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2025Article
- Time to Death and Predictors Among Neonates with Neural Tube Defects in Two Public Hospitals, Addis Ababa, Ethiopia: A Retrospective Follow-Up Study.Pediatric health, medicine and therapeutics · 2025Article
- Characteristics and predictors of chronic kidney disease in children with myelomeningocele: a nationwide cohort study.Pediatric nephrology (Berlin, Germany) · 2024Article
- Neural Tube Defect in a Resource Limited Setting: Clinical Profile and Short Term Outcome.Pediatric health, medicine and therapeutics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study is to determine the frequency of neural tube defects (NTDs) and to examine the epidemiological characteristics of NTD related deaths in Turkey.
methodsThis nationwide descriptive study was included NTD related infant deaths, termination of pregnancy for fetal anomaly (ToPFA) and stillbirth cases registered in Death Notification System between 2014 and 2019, and patients diagnosed with NTD in the 2018 birth cohort.
findingsIn the 2018 birth cohort, there were 3475 cases of NTD at birth (27.5 per 10,000). The fatality rates for live-born babies with NTD in this cohort were 13.5% at first year, and 15.6% at the end of March, 2022. NTDs were associated with 11.7% of ToPFA cases, 2.5% of stillbirths and 2.8% of infant deaths in 2014-2019. NTD related stillbirth rate was 1.74 per 10,000 births, while NTD related ToPFA rate and infant mortality rate were 0.61 and 2.70 per 10,000 live births respectively. NTD-related stillbirth and infant mortality rate were highest in the Eastern region (3.64 per 10,000 births; 4.65 per 10,000 live births respectively), while ToPFA rate was highest in the North and West regions (1.17 and 0.79 per 10,000 live births respectively) (p < 0.05). Prematurity and low birth weight were the variables with the highest NTD related rates for stillbirths (11.26 and 16.80 per 10,000 birth), ToPFA (9.25 and 12.74) per 10,000 live birth), and infant deaths (13.91 and 20.11 per 10,000 live birth) (p < 0.05).
conclusionNTDs are common and have an important place among the mortality causes in Turkey. Primary prevention through mandatory folic acid fortification should be considered both to reduce the frequency of NTD and related mortality rates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.