ArticleBMC genomics2022
Methylome and transcriptome analyses of three different degrees of albinism in apple seedlings.
Article in BMC genomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 24 citations in OpenAlex.
- Physiological, Cytological and Transcriptome Analysis of a Yellow-Green Leaf Mutant inPlants (Basel, Switzerland) · 2025Article
- Article
- Towards the Albino Mutant Gene inPlants (Basel, Switzerland) · 2024Article
- Article
- Integrated Cytological, Physiological, and Transcriptome Analyses Provide Insight into the Albino Phenotype of Chinese Plum (International journal of molecular sciences · 2023Article
- Physiological, transcriptome and co-expression network analysis of chlorophyll-deficient mutants in flue-cured tobacco.BMC plant biology · 2023Article
- Somatic Mutations in Fruit Trees: Causes, Detection Methods, and Molecular Mechanisms.Plants (Basel, Switzerland) · 2023Review
- Insights into the physiological, molecular, and genetic regulators of albinism inFrontiers in genetics · 2023Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
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Abstract
backgroundLeaf colour mutations are universally expressed at the seedling stage and are ideal materials for exploring the chlorophyll biosynthesis pathway, carotenoid metabolism and the flavonoid biosynthesis pathway in plants.
resultsIn this research, we analysed the different degrees of albinism in apple (Malus domestica) seedlings, including white-leaf mutants (WM), piebald leaf mutants (PM), light-green leaf mutants (LM) and normal leaves (NL) using bisulfite sequencing (BS-seq) and RNA sequencing (RNA-seq). There were 61,755, 79,824, and 74,899 differentially methylated regions (DMRs) and 7566, 3660, and 3546 differentially expressed genes (DEGs) identified in the WM/NL, PM/NL and LM/NL comparisons, respectively.
conclusionThe analysis of the methylome and transcriptome showed that 9 DMR-associated DEGs were involved in the carotenoid metabolism and flavonoid biosynthesis pathway. The expression of different transcription factors (TFs) may also influence the chlorophyll biosynthesis pathway, carotenoid metabolism and the flavonoid biosynthesis pathway in apple leaf mutants. This study provides a new method for understanding the differences in the formation of apple seedlings with different degrees of albinism.
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