Evidence map›Paper›PMID 35439419›Full record

ArticleNano letters2022

Implantable Aptamer-Graphene Microtransistors for Real-Time Monitoring of Neurochemical Release in Vivo.

Guangfu Wu, Nannan Zhang, Avi Matarasso, Ian Heck, Huijie Li, Wei Lu, J Glenn Phaup, Michael J Schneider, Yixin Wu, Zhengyan Weng and 14 more

Abstract read
In one paragraph

Article in Nano letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Engineering two-dimensional electronic biosensors.Nature reviews electrical engineering · 2026
    Article
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  7. Article
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  9. Review
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  11. Article
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  15. In vivo microelectrode arrays for neuroscience.Nature reviews. Methods primers · 2025
    Article
  16. Review
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Guangfu WuDepartment of Biomedical Engineering and the Institute of Materials Science, University of Connecticut, Storrs, Connecticut 06269, United States.
Nannan ZhangDalton Cardiovascular Research Center, University of Missouri, Columbia, Missouri 65211, United States.
Avi MatarassoDepartment of Bioengineering, University of Washington, Seattle, Washington 98195, United States.
Ian HeckDepartment of Biomedical, Biological, and Chemical Engineering, University of Missouri, Columbia, Missouri 65211, United States.
Huijie LiDepartment of Biomedical Engineering and the Institute of Materials Science, University of Connecticut, Storrs, Connecticut 06269, United States.
Wei LuDepartment of Materials Science and Engineering and Center for Bio-Integrated Electronics, Northwestern University, Evanston, Illinois 60208, United States.
J Glenn PhaupCenter for Precision Medicine, University of Missouri, Columbia, Missouri 65212, United States.
Michael J SchneiderDepartment of Biomedical Engineering and the Institute of Materials Science, University of Connecticut, Storrs, Connecticut 06269, United States.
Yixin WuDepartment of Materials Science and Engineering and Center for Bio-Integrated Electronics, Northwestern University, Evanston, Illinois 60208, United States.
Zhengyan WengDepartment of Biomedical Engineering and the Institute of Materials Science, University of Connecticut, Storrs, Connecticut 06269, United States.
He SunDepartment of Biomedical Engineering and the Institute of Materials Science, University of Connecticut, Storrs, Connecticut 06269, United States.
Zan GaoDepartment of Biomedical Engineering and the Institute of Materials Science, University of Connecticut, Storrs, Connecticut 06269, United States.
Xincheng ZhangDepartment of Biomedical Engineering and the Institute of Materials Science, University of Connecticut, Storrs, Connecticut 06269, United States.
Stefan G SandbergDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington 98195, United States.
Dilruba ParvinDepartment of Electrical Engineering and Computer Science, University of Missouri, Columbia, Missouri 65211, United States.
Elena SeaholmDepartment of Bioengineering, University of Washington, Seattle, Washington 98195, United States.
Syed Kamrul IslamDepartment of Electrical Engineering and Computer Science, University of Missouri, Columbia, Missouri 65211, United States.
Xueju WangDepartment of Materials Science and Engineering and the Institute of Materials Science, University of Connecticut, Storrs, Connecticut 06269, United States.ORCID 0000-0002-0669-8759
Paul E M PhillipsDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington 98195, United States.
Daniel C CastroDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, Washington 98195, United States.
Shinghua DingDalton Cardiovascular Research Center, University of Missouri, Columbia, Missouri 65211, United States.
De-Pei LiCenter for Precision Medicine, University of Missouri, Columbia, Missouri 65212, United States.
Michael R BruchasDepartment of Bioengineering, University of Washington, Seattle, Washington 98195, United States.
Yi ZhangDepartment of Biomedical Engineering and the Institute of Materials Science, University of Connecticut, Storrs, Connecticut 06269, United States.ORCID 0000-0002-0907-663X

Funding

TRAINING IN THE MOLECULAR PHARMACOLOGY OF ABUSED DRUGST32DA007278 · NIDA · UNIVERSITY OF WASHINGTON · PI Susan Marie Ferguson, Paul E. M. Phillips · 1993 to 2026
$9.8M
The Role of Gliotransmission in Cerebral IschemiaR01NS069726 · NINDS · UNIVERSITY OF MISSOURI-COLUMBIA · PI DING, SHINGHUA · 2010 to 2022
$3.3M
A Wireless, Closed-Loop Neural Probe for Optogenetics, Pharmacology and Neurochemical MonitoringRF1NS118287 · NINDS · UNIVERSITY OF CONNECTICUT STORRS · PI ZHANG, YI · 2020 to 2020
$3.3M
Neural mechanisms regulating cocaine consumptionR37DA051686 · NIDA · UNIVERSITY OF WASHINGTON · PI PHILLIPS, PAUL E. M. · 2020 to 2024
$2.5M
Mechanisms of Stress-Induced HypertensionR01HL139523 · NHLBI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LI, DE-PEI, PAN, HUI-LIN · 2018 to 2021
$1.8M
Synaptic Mechanisms of Stress-Induced HypertensionR01HL142133 · NHLBI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LI, DE-PEI, PAN, HUI-LIN · 2018 to 2021
$1.8M
Diametric changes in phasic dopamine to contingent and non-contingent drug cues in the regulation of drug taking and drug seekingR01DA039687 · NIDA · UNIVERSITY OF WASHINGTON · PI PHILLIPS, PAUL E. M. · 2015 to 2019
$1.7M
THE ROLE AND MECHANISMS OF PBEF IN ACUTE BRAIN INJURY AND LONG-TERM STROKE OUTCOMES AFTER FOCAL ISCHEMIC STROKER01NS094539 · NINDS · UNIVERSITY OF MISSOURI-COLUMBIA · PI DING, SHINGHUA · 2015 to 2019
$1.6M
Wireless, implantable optofluidic systems for programmed pharmacology and optogeneticsR42MH116525 · NIMH · NEUROLUX, INC. · PI GHAFFARI, ROOZBEH · 2019 to 2020
$1.4M
Optopharmacology and Sensors for Dissecting Opioid Action In VivoR61DA051489 · NIDA · UNIVERSITY OF WASHINGTON · PI BRUCHAS, MICHAEL R., GU, LIANGCAI · 2020 to 2022
$1.2M
NHLBI NIH HHS R01 HL139523NHLBI NIH HHS R01 HL142133NIDA NIH HHS R01 DA039687NIDA NIH HHS R37 DA051686NIDA NIH HHS R61 DA051489NIDA NIH HHS T32 DA007278NIMH NIH HHS R42 MH116525NINDS NIH HHS R01 NS069726NINDS NIH HHS R01 NS094539NINDS NIH HHS RF1 NS118287
6 · The paper itself

Abstract

The real-time monitoring of neurochemical release

Indexed as

DopamineGraphiteAnimalsMiceNorepinephrineOligonucleotidesDopamineGraphiteNorepinephrineOligonucleotidesdopaminegraphene microtransistorsneurochemical sensorsreal-time monitoring

Identifiers

PMID35439419
PMCPMC9420334

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.