Evidence map›Paper›PMID 35439412›Full record

ArticleOrganic letters2022

Intramolecular, Visible-Light-Mediated Aza Paternò-Büchi Reactions of Unactivated Alkenes.

Dominique E Blackmun, Stephen A Chamness, Corinna S Schindler

Erratum issuedAbstract read
In one paragraph

Article in Organic letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Photosensitized [4+2]- and [2+2]-Cycloaddition Reactions of N-Sulfonylimines.Angewandte Chemie (International ed. in English) · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Dominique E BlackmunDepartment of Chemistry, Willard-Henry-Dow Laboratory, University of Michigan, 930 N University Ave., Ann Arbor, Michigan 48109, United States.ORCID 0000-0002-7868-3572
Stephen A ChamnessDepartment of Chemistry, Willard-Henry-Dow Laboratory, University of Michigan, 930 N University Ave., Ann Arbor, Michigan 48109, United States.
Corinna S SchindlerDepartment of Chemistry, Willard-Henry-Dow Laboratory, University of Michigan, 930 N University Ave., Ann Arbor, Michigan 48109, United States.ORCID 0000-0003-4968-8013

Funding

Visible Light-Enabled Synthesis of Heterocycles through Energy Transfer - Equipment SupplementR01GM141340 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHINDLER, CORINNA STEFANIE · 2021 to 2024
$1.3M
NIGMS NIH HHS R01 GM141340
6 · The paper itself

Abstract

Azetidines are of particular interest in medicinal chemistry for their favorable properties, including increased resistance to oxidative metabolism and lower lipophilicity. The recent development of [2 + 2] reactions has significantly expanded the limited repertoire of methods for azetidine synthesis, but access to more complex architectures still requires further development. Herein, we report a visible-light-enabled intramolecular [2 + 2] cycloaddition of unactivated alkenes that proved previously unreactive to access tricyclic azetidines with 3D complex structures and high levels of saturation.

Indexed as

AlkenesAzetidinesCycloaddition ReactionLightAlkenesAzetidines

Identifiers

PMID35439412
PMCPMC10339342

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.