Evidence map›Paper›PMID 35439409›Full record

ArticleJournal of the American Chemical Society2022

Surprising Rigidity of Functionally Important Water Molecules Buried in the Lipid Headgroup Region.

Rongfu Zhang, Timothy A Cross, Xinhua Peng, Riqiang Fu

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Journal of magnetic resonance (San Diego, Calif. : 1997) · 2026
    Article
  3. Review
  4. Review
  5. The journal of physical chemistry. A · 2025
    Article
  6. Hydraulic Activation of the AsLOV2 Photoreceptor.bioRxiv : the preprint server for biology · 2025
    Article
  7. Review
  8. Article
  9. Expanding the Toolset of Biomolecular NMR with Efficient and Cost-EffectiveChemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  10. Cholesterol Changes Interfacial Water Alignment in Model Cell Membranes.Journal of the American Chemical Society · 2024
    Article
  11. The journal of physical chemistry. B · 2024
    Review
  12. Article
  13. Article
  14. Laurdan Discerns Lipid Membrane Hydration and Cholesterol Content.The journal of physical chemistry. B · 2023
    Article
  15. Magnetically aligned nanodiscs enable direct measurement ofJournal of magnetic resonance (San Diego, Calif. : 1997) · 2023
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Rongfu ZhangNational High Magnetic Field Laboratory, 1800 East Paul Dirac Drive, Tallahassee, Florida 32310, United States.
Timothy A CrossNational High Magnetic Field Laboratory, 1800 East Paul Dirac Drive, Tallahassee, Florida 32310, United States.ORCID 0000-0002-9413-0505
Xinhua PengCAS Key Laboratory of Microscale Magnetic Resonance and Department of Modern Physics, University of Science and Technology of China, Hefei 230026, China.
Riqiang FuNational High Magnetic Field Laboratory, 1800 East Paul Dirac Drive, Tallahassee, Florida 32310, United States.ORCID 0000-0003-0075-0410
Florida State University · USUniversité Bourgogne Franche-Comté · FRUniversity of Science and Technology of China · CN

Funding

TR&D3-SCHP41GM122698 · NIGMS · FLORIDA STATE UNIVERSITY · PI BREY, WILLIAM W, CROSS, TIMOTHY A · 2017 to 2021
$6.7M
NIGMS NIH HHS P41 GM122698
6 · The paper itself

Abstract

Understanding water dynamics and structure is an important topic in biological systems. It is generally held in the literature that the interfacial water of hydrated phospholipids is highly mobile, in fast exchange with the bulk water ranging from the nano- to femtosecond timescale. Although nuclear magnetic resonance (NMR) is a powerful tool for structural and dynamic studies, direct probing of interfacial water in hydrated phospholipids is formidably challenging due to the extreme population difference between bulk and interfacial water. We developed a novel

Indexed as

DimyristoylphosphatidylcholineWaterLipid BilayersMagnetic Resonance SpectroscopyPhospholipidsDimyristoylphosphatidylcholineLipid BilayersPhospholipidsWater

Identifiers

PMID35439409
PMCPMC9165019
OpenAlexW4224228901

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.