Evidence map›Paper›PMID 35438978›Full record

ArticleACS synthetic biology2022

Synthetic Translational Regulation by Protein-Binding RNA Origami Scaffolds.

Michael T A Nguyen, Georgios Pothoulakis, Ebbe S Andersen

Open access · bronzeAbstract read
In one paragraph

Article in ACS synthetic biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michael T A NguyenInterdisciplinary Nanoscience Center, Aarhus University, 8000 Aarhus C, Denmark.
Georgios PothoulakisInterdisciplinary Nanoscience Center, Aarhus University, 8000 Aarhus C, Denmark.
Ebbe S AndersenInterdisciplinary Nanoscience Center, Aarhus University, 8000 Aarhus C, Denmark.ORCID 0000-0002-6236-8164
Aarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rational design approaches for the regulation of gene expression are expanding the synthetic biology toolbox. However, only a few tools for regulating gene expression at the translational level have been developed. Here, we devise an approach for translational regulation using the MS2 and PP7 aptamer and coat-protein pairs in

Indexed as

RNASynthetic BiologyEscherichia coliProtein BindingProtein BiosynthesisRNApost-transcriptional regulationRNA origamiRNA-protein complexesRNA synthetic biology

Identifiers

PMID35438978
PMCPMC9127956
OpenAlexW4224305882

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.