Evidence map›Paper›PMID 35438647›Full record

ArticleJMIR research protocols2022

The Effectiveness and Cost-effectiveness of Well Parent Japan for Japanese Mothers of Children With ADHD: Protocol for a Randomized Controlled Trial.

Shizuka Shimabukuro, David Daley, Takahiro Endo, Satoshi Harada, Akemi Tomoda, Yushiro Yamashita, Takashi Oshio, Boliang Guo, Atsuko Ishii, Mio Izumi and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JMIR research protocols, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Shizuka ShimabukuroHuman Developmental Neurobiology Unit, Okinawa Institute of Science and Technology Graduate University, Onna-son, Okinawa, Japan.ORCID https://orcid.org/0000-0003-2899-2788
David DaleyDivision of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham UK, Nottingham, United Kingdom.ORCID https://orcid.org/0000-0002-3597-0408
Takahiro EndoNational Hospital Organization Ryukyu Hospital, Kin-Town Kunigami-gun Okinawa, Japan.ORCID https://orcid.org/0000-0003-2230-688X
Satoshi HaradaNational Hospital Organization Ryukyu Hospital, Kin-Town Kunigami-gun Okinawa, Japan.ORCID https://orcid.org/0000-0001-9620-702X
Akemi TomodaResearch Center for Child Mental Development, University of Fukui, Fukui, Japan.ORCID https://orcid.org/0000-0002-6558-5017
Yushiro YamashitaDepartment of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Japan.ORCID https://orcid.org/0000-0001-8677-3183
Takashi OshioInstitute of Economic Research, Hitotsubashi University, Tokyo, Japan.ORCID https://orcid.org/0000-0001-8142-5585
Boliang GuoDivision of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham UK, Nottingham, United Kingdom.ORCID https://orcid.org/0000-0002-1844-705X
Atsuko IshiiUnited Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University and University of Fukui, Osaka University, Yamadaoka Suita, Osaka, Japan.ORCID https://orcid.org/0000-0001-5346-6881
Mio IzumiNational Hospital Organization Ryukyu Hospital, Kin-Town Kunigami-gun Okinawa, Japan.ORCID https://orcid.org/0000-0003-2451-4391
Yukiko NakaharaDepartment of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Japan.ORCID https://orcid.org/0000-0001-6397-0141
Kazushi YamamotoDepartment of Child and Adolescent Psychological Medicine, University of Fukui Hospital, Fukui, Japan.ORCID https://orcid.org/0000-0003-1446-8715
Akiko YaoResearch Center for Child Mental Development, University of Fukui, Fukui, Japan.ORCID https://orcid.org/0000-0001-8707-5037
Gail TrippHuman Developmental Neurobiology Unit, Okinawa Institute of Science and Technology Graduate University, Onna-son, Okinawa, Japan.ORCID https://orcid.org/0000-0002-3622-4714
National Hospital Organization · JPUniversity of Fukui · JPKurume University · JPOkinawa Institute of Science and Technology Graduate University · JPUniversity of Nottingham · GBHitotsubashi University · JPUniversity of Fukui Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAttention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder associated with numerous functional deficits and poor long-term outcomes. Internationally, behavioral interventions are recommended as part of a multimodal treatment approach for children with ADHD. Currently, in Japan, there are limited interventions available to target ADHD. Well Parent Japan (WPJ), a new hybrid parent-training program, provides a culturally acceptable and effective way to help support Japanese children with ADHD and their parents.

objectiveThis pragmatic multicenter randomized controlled trial aims to provide preliminary evidence about the effectiveness and cost-effectiveness of WPJ evaluated against treatment as usual (TAU) within routine Japanese mental health services.

methodsMothers of children (aged 6-12 years) diagnosed with ADHD were recruited from child and adolescent mental health care services at three hospital sites across Japan (Fukui, Fukuoka, and Okinawa). The mothers were randomized to receive immediate treatment or TAU. The effectiveness and cost-effectiveness of WPJ over TAU at the end of the intervention and at 3-month follow-up will be evaluated. The primary outcome is maternal parent domain stress in the parenting role. The following secondary outcomes will be explored: child behavior, including severity of ADHD symptoms; parenting practices; emotional well-being; and the parent-child relationship and maternal child domain parenting stress. Data analysis will follow intention-to-treat principles with treatment effects quantified through analysis of covariance using multilevel modeling. An incremental cost-effectiveness ratio will be used to analyze the cost-effectiveness of the WPJ intervention.

resultsStudy funding was secured through a proof-of-concept grant in July 2018. Approval by the institutional review board for the data collection sites was obtained between 2017 and 2019. Data collection began in August 2019 and was completed in April 2022. Participant recruitment (N=124) was completed in May 2021. Effectiveness and cost-effectiveness analyses are expected to be completed by July 2022 and December 2022, respectively. These timelines are subject to change owing to the COVID-19 pandemic.

conclusionsThis is the first multisite pragmatic trial of WPJ based on the recruitment of children referred directly to routine clinical services in Japan. This multisite randomized trial tests the effectiveness of WPJ in children and families by comparing WPJ directly with the usual clinical care offered for children diagnosed with ADHD in Japan. We also seek to assess and compare the cost-effectiveness of WPJ with TAU in Japan.

trial registrationInternational Standard Randomised Controlled Trial Number ISRCTN66978270; https://www.isrctn.com/ISRCTN66978270. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/32693.

Indexed as

ADHDJapanNew Forest Parent Programmeparent stress managementparent training

Identifiers

PMID35438647
PMCPMC9066326
OpenAlexW4210739992

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.