Evidence map›Paper›PMID 35438610›Full record

ArticleAmerican journal of respiratory and critical care medicine2022

The Proteomic Profile of Interstitial Lung Abnormalities.

Gisli Thor Axelsson, Gunnar Gudmundsson, Katherine A Pratte, Thor Aspelund, Rachel K Putman, Jason L Sanders, Elias F Gudmundsson, Hiroto Hatabu, Valborg Gudmundsdottir, Alexander Gudjonsson and 11 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 3 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Article
  5. The impact of low-frequency genetic variants on serum protein levels.bioRxiv : the preprint server for biology · 2026
    Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Mechanistic Insights into Tumorigenesis from Serum Proteins.medRxiv : the preprint server for health sciences · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 8 institutions in 3 countries.

Gisli Thor AxelssonFaculty of Medicine, University of Iceland, Reykjavik, Iceland.ORCID 0000-0002-7156-9080
Gunnar GudmundssonFaculty of Medicine, University of Iceland, Reykjavik, Iceland.
Katherine A PratteNational Jewish Health, Denver, Colorado.
Thor AspelundFaculty of Medicine, University of Iceland, Reykjavik, Iceland.
Rachel K PutmanPulmonary and Critical Care Division.
Jason L SandersPulmonary and Critical Care Division.
Elias F GudmundssonIcelandic Heart Association, Kopavogur, Iceland.
Hiroto HatabuDepartment of Radiology, and.
Valborg GudmundsdottirFaculty of Medicine, University of Iceland, Reykjavik, Iceland.
Alexander GudjonssonIcelandic Heart Association, Kopavogur, Iceland.
Takuya HinoCenter for Pulmonary Functional Imaging, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Tomoyuki HidaCenter for Pulmonary Functional Imaging, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Brian D HobbsPulmonary and Critical Care Division.
Michael H ChoPulmonary and Critical Care Division.
Edwin K SilvermanPulmonary and Critical Care Division.
Russell P BowlerNational Jewish Health, Denver, Colorado.
Lenore J LaunerLaboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, Maryland; and.
Lori L JenningsNovartis Institutes for Biomedical Research, Cambridge, Massachusetts.
Gary M HunninghakePulmonary and Critical Care Division.
Valur EmilssonIcelandic Heart Association, Kopavogur, Iceland.
Vilmundur GudnasonFaculty of Medicine, University of Iceland, Reykjavik, Iceland.
Brigham and Women's Hospital · USUniversity of Iceland · ISIcelandic Heart Association · ISNational Jewish Health · USPulmonary and Critical Care Associates · USBoston Biomedical Research Institute · USNational Institute on Aging · USReykjavík University · IS

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Respiratory Computational Discovery CoreP01HL114501 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHOI, MARY E · 2013 to 2025
$24.9M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
Peripheral Markers of Phenotypic Heterogeneity in COPDP50HL084948 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCIURBA, FRANK · 2007 to 2012
$12.8M
The Boston Lung Cancer Survival CohortU01CA209414 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI David C Christiani · 2017 to 2026
$12.2M
Clinical Genetics and Screening for Pulmonary FibrosisR01HL130974 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GARY MATTHEW HUNNINGHAKE, Benjamin Alexander Raby · 2016 to 2026
$10.0M
Genetic and Genomic Characterization of the Occurrence and Progression of Interstitial Lung AbnormalitiesR01HL135142 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MICHAEL H. CHO, GARY MATTHEW HUNNINGHAKE · 2017 to 2026
$7.7M
Interstitial Lung Abnormalities: Defining the Phenotype, Causes, and Consequences.R01HL111024 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI HUNNINGHAKE, GARY MATTHEW · 2013 to 2022
$6.4M
CLINICAL PROJECT: Age, Gene/Environment Susceptibility Study on the Multi-omics of Aging: A clinical epidemiologic prospective studyZIAAG007380 · NIA · NATIONAL INSTITUTE ON AGING · PI LAUNER, LENORE J · 2009 to 2025
$6.1M
Identifying Genetic Determinants of Severe, Early-Onset COPDR01HL113264 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHO, MICHAEL H., SILVERMAN, EDWIN K · 2012 to 2016
$6.0M
Identifying functional variants in COPD GWAS lociR01HL137927 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHO, MICHAEL H., SILVERMAN, EDWIN K · 2017 to 2020
$3.5M
Biomarker of Lung Disease in African AmericansR01HL137995 · NHLBI · NATIONAL JEWISH HEALTH · PI BOWLER, RUSSELL PAUL, KECHRIS-MAYS, KATHERINA · 2018 to 2021
$3.4M
NCI NIH HHS R01 CA203636NCI NIH HHS U01 CA209414NHLBI NIH HHS K08 HL136928NHLBI NIH HHS K08 HL140087NHLBI NIH HHS P01 HL114501NHLBI NIH HHS P50 HL084948NHLBI NIH HHS P50HL084948NHLBI NIH HHS R01 HL111024NHLBI NIH HHS R01 HL113264NHLBI NIH HHS R01 HL129937NHLBI NIH HHS R01 HL130974NHLBI NIH HHS R01 HL135142NHLBI NIH HHS R01 HL137927NHLBI NIH HHS R01 HL137995NHLBI NIH HHS R01 HL152735NHLBI NIH HHS R21 HL129917NHLBI NIH HHS R21HL129917NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897NIH HHS 5U01CA209414-03NIH HHS HHSN27120120022CNIH HHS K08 HL136928NIH HHS K08 HL140087NIH HHS N01-AG-1-2100NIH HHS P01 HL114501NIH HHS R01 133135NIH HHS R01 135142NIH HHS R01 137927NIH HHS R01CA203636NIH HHS R01 HL111024NIH HHS R01 HL113264NIH HHS R01 HL130974NIH HHS R01 HL135142NIH HHS R01 HL137927NIH HHS R01 HL137995NIH HHS R01 HL152735NIH HHS U01 HL089856
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lung Diseases, InterstitialRespiratory System AbnormalitiesGenetic Predisposition to DiseaseHumansLungProspective StudiesProteomicsTomography, X-Ray Computedbiomarkersidiopathic pulmonary fibrosisinterstitial lung abnormalitiesinterstitial lung diseaseproteomics

Identifiers

PMID35438610
PMCPMC9890263
OpenAlexW4224214010

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.