Evidence map›Paper›PMID 35438391›Full record

ArticleNeurotoxicity research2022

The Impact of the Antipsychotic Medication Chlorpromazine on Cytotoxicity through Ca

Che-Sheng Chu, Yung-Shang Lin, Wei-Zhe Liang

Abstract read
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In one paragraph

Article in Neurotoxicity research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The Janus face of antipsychotics in glial cells: Focus on glioprotection.Experimental biology and medicine (Maywood, N.J.) · 2023
    Review
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Che-Sheng ChuDepartment of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, 81362, Taiwan.
Yung-Shang LinDepartment of Neurosurgery, Kaohsiung Veterans General Hospital, Kaohsiung, 81362, Taiwan.
Wei-Zhe LiangDepartment of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, 81362, Taiwan. lianggoole67@gmail.com.ORCID http://orcid.org/0000-0001-7131-6377
Kaohsiung Veterans General Hospital · TWTajen University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chlorpromazine, an antipsychotic medication, is conventionally applied to cope with the psychotic disorder such as schizophrenia. In cellular studies, chlorpromazine exerts many different actions through calcium ion (Ca

Indexed as

Antipsychotic AgentsCalcium SignalingApoptosisCalciumCell Line, TumorCell SurvivalChelating AgentsChlorpromazineHumansNeurogliaThapsigarginType C PhospholipasesAntipsychotic AgentsCalciumChelating AgentsChlorpromazineThapsigarginType C PhospholipasesCa2+ signalingChlorpromazineCytotoxicityEndoplasmic reticulumGlial cell modelsStore-operated Ca2+ entry

Identifiers

PMID35438391
OpenAlexW4224215586

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.