ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2022
Making the Diagnosis in Sagittal Craniosynostosis-It's Height, Not Length, That Matters.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Renier H-cranioplasty Modifies Skull Shape More Than Total Vault Remodeling in Nonsyndromic Scaphocephaly: Artificial Intelligence-based Study.Plastic and reconstructive surgery. Global open · 2026Article
- Quantifying Sagittal Craniosynostosis Severity: A Machine Learning Approach With CranioRate.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026Article
- Two-Year Progressive Cranial Changes Following the Melbourne Technique for Sagittal Craniosynostosis.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026Article
- The Use of Machine Learning to Enable Objective Assessment of Surgical Outcomes in Sagittal Craniosynostosis.Plastic and reconstructive surgery. Global open · 2026Article
- A coddling of the sagittal suture: inequality in spring-assisted expansion.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Radiomorphologic profiles of nonsyndromic sagittal craniosynostosis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
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8 authors.
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Abstract
introductionThis study assesses the diagnostic reliability of a novel photogrammetric measurement to distinguish sagittal craniosynostosis (SS) from control and false positive cases (SNS).
methodsHead CTs from 2014-2020 were reviewed for patients with sagittal synostosis (SS, n = 177), presumed sagittal synostosis with normal imaging (SNS, n = 30), and controls (n = 100). Using preoperative clinical photographs and CTs, a measurement reflecting the anterior-posterior location of the vertex was measured using an angle drawn between the cranial vertex, nasion, and opisthocranion (VNO) in profile view, with the head in a neutral position.
resultsMean age at pre-operative head CT was 9.5 months for the SS cohort, 4.2 months for the SNS cohort, and 8.9 months for controls (p = .327). Mean age at pre-operative clinical photograph was 9.5 months for the SS cohort and 4.2 months for the SNS cohort (p = .149). Pearson correlations revealed no significant association between age and VNO angle. The average VNO angle measured on clinical photographs was 54.7° ± 3.8° for the SS group, 43.1° ± 2.2° for the SNS group, and 41.1° ± 3.7° for controls (p < .001). Receiver operating characteristic (ROC) analysis yielded a cut-off of ≥ 50° to identify SS. Diagnostic sensitivity and specificity were 96.6% and 99.2%, respectively. Three-rater analysis yielded an average ICC of 0.742 (p = .004).
conclusionsMeasurement of the VNO angle is a reliable screening tool to diagnose sagittal craniosynostosis, with an angle of 50° or more suggesting suture synostosis. This method relies on the relationship between the anterior displacement of the vertex and occipital bulleting to approach the diagnostic accuracy of CT imaging.
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