ArticleInternational journal of methods in psychiatric research2022
Familial factors, depression and cognitive decline: A longitudinal mediation analysis based on latent growth modeling (LGM).
Article in International journal of methods in psychiatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 11 citations in OpenAlex.
- Association between social activity participation and rural-urban difference in depressive symptoms among middle-aged and older adults in China: a Fairlie decomposition analysis.BMC public health · 2026Article
- Clustering and modeling joint-trajectories of HIV/AIDS and tuberculosis mortality rates using bayesian multi-process latent growth model: A global study from 1990 to 2021.BMC infectious diseases · 2025Article
- Gardening and subjective cognitive decline: a cross-sectional study and mediation analyses of 136,748 adults aged 45+ years.Nutrition journal · 2024Article
- Familial factors, depression and cognitive decline: A longitudinal mediation analysis based on latent growth modeling (LGM).International journal of methods in psychiatric research · 2022Article
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3 authors at 1 institution in 1 country.
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Abstract
backgroundCognitive decline of ageing population has become one of the major public health challenges worldwide, and familial factors (such as household income, marital status, etc.) have been identified as risk factors. Currently, we mainly focused on two familial factors: living with spouse/child and intergenerational rearing (taking care of grandchildren), exploring their relations with cognitive ageing. We also tested the possible mediating role of depression between the two family factors and cognitive decline.
methodsData was derived from China Health and Retirement Longitudinal Study (CHARLS) database, and a total of 8474 participants (3602 females, mean age = 69.64) were included in the current research. Latent growth model (LGM) has been constructed for cognitive functions, with initial level and declining rate being estimated respectively. We further examined: (1) whether living with spouse/child and intergenerational rearing could influence the declining trajectory (initial level and declining rate) of elders' cognitive functioning; (2) and if so, whether depression could mediate the effects of living with spouse/child and intergenerational rearing on cognitive functioning.
resultsFirst, while living with spouse/child was related to higher initial level of cognitive functions and slower declining rate, intergenerational rearing was associated with neither of them. Second, growth trajectory of depression partly mediated the effects of living with spouse/child on cognitive functioning (Indirect effect = 0.14; p < 0.01).
conclusionsFamilial factors (living with spouse/child and intergenerational rearing) may be influential on declining trajectories of elders' cognitive functions, and depression may mediate such effects. More research efforts are needed to investigate the mechanisms underlying the relations between familial factors and cognitive ageing.
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