Evidence map›Paper›PMID 35438156›Full record

ArticleInteractive cardiovascular and thoracic surgery2022

Surgical and interventional rescue strategies for Fontan failure.

Gregor Gierlinger, Eva Sames-Dolzer, Michaela Kreuzer, Roland Mair, Mohammad-Paimann Nawrozi, Andreas Tulzer, Christoph Bauer, Gerald Tulzer, Rudolf Mair

Open access · bronzeAbstract read
In one paragraph

Article in Interactive cardiovascular and thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Hraska procedure for failing Fontan circulation.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Gregor GierlingerDivision of Pediatric and Congenital Heart Surgery, Kepler University Hospital, Linz, Austria.ORCID 0000-0002-6358-5048
Eva Sames-DolzerDivision of Pediatric and Congenital Heart Surgery, Kepler University Hospital, Linz, Austria.
Michaela KreuzerDivision of Pediatric and Congenital Heart Surgery, Kepler University Hospital, Linz, Austria.
Roland MairDivision of Pediatric and Congenital Heart Surgery, Kepler University Hospital, Linz, Austria.ORCID 0000-0002-0006-2098
Mohammad-Paimann NawroziDepartment for Thoracic and Cardiovascular Surgery, Kepler University Hospital, JKU, Linz, Austria.
Andreas TulzerMedical Faculty, Johannes Kepler University Linz, Linz, Austria.
Christoph BauerMedical Faculty, Johannes Kepler University Linz, Linz, Austria.ORCID 0000-0001-7350-1189
Gerald TulzerDepartment of Pediatric Cardiology, Kepler University Hospital, JKU, Linz, Austria.ORCID 0000-0003-0473-0257
Rudolf MairDivision of Pediatric and Congenital Heart Surgery, Kepler University Hospital, Linz, Austria.ORCID 0000-0003-0935-1766
Johannes Kepler University of Linz · ATKepler Universitätsklinikum · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesFontan patients are at lifelong risk for developing complications, which may result in Fontan failure. Survival rates after heart transplantation (HTX) are still unsatisfying in these patients. Long-term survival of extracardiac Fontan patients in the modern era was investigated. The objective of this study was to investigate if surgical and interventional procedures in patients with protein-losing enteropathy (PLE) and/or plastic bronchitis (PB) and a failing Fontan circulation can postpone or avoid HTX.

methodsRetrospective data collection of all children who underwent a Fontan procedure between January 1999 and July 2021 at our centre was performed. Patients were surveyed regarding the occurrence of PLE or PB and their outcome was reported descriptively. HTX-free survival of patients who underwent a rescue procedure due to PLE/PB was evaluated.

resultsThree hundred and seventy [94.1% (95% confidence interval, 91.4-96.3)] Fontan patients were free of HTX or death at last follow-up after a median follow-up time of 6.7 years. PB/PLE was diagnosed in 34 patients during the observation period. A rescue procedure was undertaken in 16 pts. at a median time of 6.5 months (range: 1 day to 9.4 years) since the initial diagnosis of PLE/PB. In these patients, HTX-free survival was 75% (95% confidence interval, 47.6-92.7) at a median follow-up time of 4.0 years after the procedure. Range: 3.5 months to 13.9 years.

conclusionsExtracardiac Fontan patients in the modern era expect reasonable HTX-free survival rates. Surgical and/or interventional rescue strategies for Fontan failure can postpone HTX for a sustained period of time.

Indexed as

BronchitisFontan ProcedureHeart Defects, CongenitalHeart TransplantationProtein-Losing EnteropathiesChildHumansPostoperative ComplicationsRetrospective StudiesRisk FactorsTreatment OutcomeFontan failureFontan operationPlastic bronchitisProtein-losing enteropathySingle ventricle palliation

Identifiers

PMID35438156
PMCPMC9419686
OpenAlexW4224267640

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.