Evidence map›Paper›PMID 35437835›Full record

ReviewReproduction in domestic animals = Zuchthygiene2022

Embryo biotechnologies in sheep: Achievements and new improvements.

Laura Falchi, Sergio Ledda, Maria T Zedda

Open access · greenAbstract readReview
In one paragraph

Review in Reproduction in domestic animals = Zuchthygiene, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The current status of artificial reproductive technologies in sheep.The Journal of reproduction and development · 2026
    Review
  9. Article
  10. Article
  11. Animal reproduction · 2026
    Article
  12. Breed and Season: Key Determinants of Efficiency in Large-Scale CommercialAnimals : an open access journal from MDPI · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Animal reproduction · 2023
    Review
  20. Embryo biotechnologies in sheep: Achievements and new improvements.Reproduction in domestic animals = Zuchthygiene · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Laura FalchiSezione di Cl. Ostetrica e Ginecologia, Dipartimento di Medicina Veterinaria, Università degli Studi di Sassari, Sassari, Italy.ORCID https://orcid.org/0000-0003-0927-8220
Sergio LeddaSezione di Cl. Ostetrica e Ginecologia, Dipartimento di Medicina Veterinaria, Università degli Studi di Sassari, Sassari, Italy.ORCID https://orcid.org/0000-0002-9779-5684
Maria T ZeddaSezione di Cl. Ostetrica e Ginecologia, Dipartimento di Medicina Veterinaria, Università degli Studi di Sassari, Sassari, Italy.
University of Sassari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To date, large-scale use of multiple ovulation and embryo transfer (MOET) programmes in ovine species is limited due to unpredictable results and high costs of hormonal stimulation and treatment. Therefore, even if considered reliable, they are not fully applicable in large-scale systems. More recently, the new prospects offered by in vitro embryo production (IVEP) through collection of oocytes post-mortem or by repeated ovum pick-up from live females suggested an alternative to MOET programmes and may be more extensively used, moving from the exclusive research in the laboratory to field application. The possibility to perform oocytes recovery from juvenile lambs to obtain embryos (JIVET) offers the great advantage to significantly reduce the generation interval, speeding the rate of genetic improvement. Although in the past decades several studies implemented novel protocols to enhance embryo production in sheep, the conditions of every single stage of IVEP can significantly affect embryo yield and successful transfer into the recipients. Moreover, the recent progresses on embryo production and freezing technologies might allow wider propagation of valuable genes in small ruminants populations and may be used for constitution of flocks without risks of disease. In addition, they can give a substantial contribution in preserving endangered breeds. The new era of gene editing might offer innovative perspectives in sheep breeding, but the application of such novel techniques implies involvement of specialized operators and is limited by relatively high costs for embryo manipulation and molecular biology analysis.

Indexed as

Embryo, MammalianEmbryo TransferAnimalsBiotechnologyFemaleFertilization in VitroOocytesReproductionSheepeweIVEPLOPUoocyte competencerecipienttransfer

Identifiers

PMID35437835
PMCPMC9790389
OpenAlexW4224237389

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.